Chiesi Farmaceutici S.p.a.

Università Degli Studi Di Parma

Laboratorio Italiano Biochimico Farmaceutico Lisapharma S.p.a.

Pier Luigi Catellani

Paolo Colombo

Ruggero Bettini

Paolo Ventura

Giovanni Caponetti

Patrizia Santi

Gaia Colombo

An innovative pharmaceutical form for controlled drug release relates to systems obtained by the assembly of individual release modules, of which the capacity to release the drug in time and in space depends on the way in which the modules have been assembled. The modular structure offers high reproducibility of manufacture and flexibility of release.

Modular systems for the controlled release of a substance with space and time control

Carrier particles, for use in the preparation of powdery mixtures for administration by inhalation, and having a median diameter of greater than 90 microns and a surface rugosity expressed as the fractal dimension of less than or equal to 1.1, may be prepared by subjecting particles having a median diameter of greater than 90 microns to repeated stages of wetting with a solvent and drying.

Powder particles with smooth surface for use in inhalation therapy

Carriers for use in the preparation of mixtures for inhalation powders intended for pulmonary administration of micronized drugs by means of a dry powder inhaler and the method for their preparation are described.

Growing community of inventors

Reggio Emilia, Italy

Pier Luigi Catellani