Duke University

Biospecifics Technologies Corporation

Johns Hopkins University

North Carolina Central University

Endo Biologics, Inc.

Phyllis Carolyn Leppert

Thomas L Wegman

Darlene K Taylor

James H Segars

Jean-Marie Soma

Disclosed herein are compositions and methods for treating uterine fibroids in vivo, and methods of reducing symptoms associated with uterine fibroids, including pain, bleeding and infertility. The disclosed compositions comprise collagenase in an amount effective to cause shrinkage and/or reduce stiffness of uterine fibroids.

Treatment of uterine fibroids using purified collagenase

Compositions and methods for treating uterine fibroids are described, wherein a uterine fibroid treatment agent comprising collagenase in an amount effective to cause shrinkage of uterine fibroids is injected or inserted into the uterine fibroid.

Treatment method and product for uterine fibroids using purified collagenase

The invention relates to compositions and methods for treating uterine fibroids, wherein a uterine fibroid treatment agent comprising collagenase in an amount effective to cause shrinkage of uterine fibroids is injected or inserted into the uterine fibroid.

Growing community of inventors

Durham, NC, United States of America

Phyllis Carolyn Leppert