Arizona State University

Arizona Board of Regents, a Body Corporate

Whittemore Peterson Institute

Phillip Stafford

Stephen Albert Johnston

Neal W T Woodbury

Vincent C Lombardi

Neal Woodbury

The present application provides arrays for use in immunosignaturing and quality control of such arrays. Also disclosed are peptide arrays and uses thereof for diagnostics, therapeutics and research.

Peptide array quality control

The invention provides arrays of compound for use in profiling samples. The arrays include compounds bind to components of the samples at relatively low affinities. The avidity of compounds binding to components of the samples can be increased by forming arrays such that multivalent components of the samples (e.g., antibodies or cells) can bind to more than one molecule of a compound at the same time. When a sample is applied to an array under such conditions, the compounds of the array bind to component(s) of the sample with significantly different avidities generating a profile characteristic of the sample.

Compound arrays for sample profiling

Described herein are methods and devices for diagnosing chronic fatigue syndrome using peptide arrays, and providing a prognosis to patients.

Growing community of inventors

Phoenix, AZ, United States of America

Phillip Stafford