Honeywell International Inc.

Ativa Medical Corporation

Phillip Henning

Pamela Wong

Elizabeth Palaima

Eric Richard Peltola

Daniel R McPeak

Ka Man Lee

Apparatus, system and method for dispensing a particle-laden fluid from a fluid holding and dispensing micro-feature and/or multiple lysing channel structures. In some implementations, the apparatus includes: a chamber having one or more surfaces that define a volume to receive fluid containing particulate matter, a soluble surface coating on a portion of the one or more surfaces of the chamber, and an outlet port to dispense at least a portion of the fluid from the chamber. In some implementations, the particle-laden fluid may be whole blood, and the soluble surface coating may include reagents and/or dyes that are diffused into the whole blood received within the chamber to generate signals to visualize various cellular components. In some implementations, the apparatus may also include a second soluble surface coating on portions of surfaces of the multiple lysing channel structures.

Fluid holding and dispensing micro-feature

A multiple polymer layer test cartridge includes an input to receive a sample containing cells, multiple lysing channel structures on alternate layers of the multiple layer test cartridge coupled to each other to pass the sample in sequence between the lysing channel structures, and a test chamber to receive the sample from the multiple lysing channel structures.

Polymer test cartridge mixer for cell lysis

Growing community of inventors

Minneapolis, MN, United States of America

Phillip Henning