Icubate, Inc.

Adtran Gmbh

Phillip Ewing

Jian Han

Jeff Bertrand

Marc L Roth

Paul L Wooten

Embodiments of the present disclosure generally pertain to systems and methods for performing amplicon rescue multiplex polymerase chain reaction (arm-PCR). In one embodiment, the system comprises a processor and a reader coupled to a control element. The control element is configured to control the operation of the processor and the reader based on a variety of settings. The processor is configured to receive a self-contained cassette for performing PCR amplification of DNA and/or RNA obtained from an organic specimen. The processor engages with the cassette and manipulates reagents within the cassette in order to amplify and detect the DNA from the specimen. The processor also causes the cassette to deposit the DNA on a microarray within the cassette. The reader is configured to receive the cassette after it has been processed by the processor and to capture an image of the microarray for transmission to the control element as test data. The control element is further configured to analyze the test data received from the reader and to produce an output indicative of a comparison of the test data to predefined data.

Systems and methods for performing amplicon rescue multiplex polymerase chain reaction (PCR)

A test fixture interfaces plural units under test (UUTs) with test equipment within a common equipment rack. The test fixture supports a plurality of vertically spaced apart shelf units. A shelf unit has a support surface and an input/output connector panel adjacent thereto, that define a UUT insertion cavity. An input/output connector panel contains cable terminations that terminate cables to various testing equipments. Insertion of a UUT into the insertion cavity places communication ports of the UUT adjacent to cable terminations of the adjacent input/output connector panel. Jumper cables interconnect communication ports of the UUT with cable terminations of the adjacent input/output connector panel.

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Madison, AL, United States of America

Phillip Ewing