The Procter Gamble Company

Phillip Asa Drake

George Endell Deckner

Ruzhan Peng

William Michael Glandorf

Douglas Craig Scott

John Patrick Herlinger

Richard Craig Maupin

Mark Steven Leusch

Tiffany Celeste Hare

Colleen Mary McSwiggin

George Endel Deckner

Comparative effectiveness of various oral care products such as dentifrices on preventing dental erosion may be demonstrated using simulated enamel. A substrate is prepared. A mineral layer to simulate dental enamel is nucleated by solution growth on the substrate surface. Alternatively, the mineral layer may be nucleated on a template comprising a self-assembled monolayer formed on a gold layer deposited on the substrate surface. The mineral layer may comprise a homogeneous layer of hydroxyapatite or a thin veneer of hydroxyapatite on a layer of amorphous calcium phosphate. The simulated enamel is then optionally treated with an oral care product and subjected to an acid challenge. The amount of mineral layer remaining after the acid challenge illustrates the effectiveness or non-effectiveness of the oral care product at preventing dental erosion.

Apparatus and methods for visual demonstration of dental erosion on simulated dental materials

A method and device for visually recording hydraulic conductance through a sectioned piece of dentin; and which can be used to measure the effectiveness of treatments to reduce the permeability of dentin.

Method and device for measuring dentin permeability

The present invention relates to oral care compositions, including therapeutic rinses, tooth pastes and gels comprising a combination of a non-cariogenic carbohydrate and polyalcohol. This invention further relates to a method for treating or preventing conditions in the mouth that favor formation of tooth caries.

Anti-caries oral care compositions and their methods of use

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Mason, OH, United States of America

Phillip Asa Drake