Biota Scientific Management Pty Ltd

Phillip A Reece

Keith G Watson

Betty Jin

Guy Y Krippner

Wen-Yang Wu

Simon P Tucker

This invention relates to a compound capable of binding to a picornavirus capsid comprising two or more capsid binding moieties.

Antiviral agents

The invention provides novel macromolecules, methods for their preparation, pharmaceutical formulations thereof and their use as anti-influenza agents. The invention also provides a novel diagnostic method which can be used for detection of all types of influenza A and B virus. The macromolecular compound of the invention has attached to it one or more molecules (neuraminidase binders) which bind to the active site of influenza virus neuraminidase but which are not cleaved by the neuraminidase.

Macromolecular neuraminidase-binding compounds

The invention provides a method of detection of influenza virus which utilizes compounds able to bind specifically to the active site of influenza virus neuraminidase, and novel compounds for use in the method.

Growing community of inventors

Balwyn, Australia

Phillip A Reece