Institut National De La Sante Et De La Recherche Medicale

Université Paul Sabatier (toulouse Iii)

Centre Hospitalier Universitaire De Toulouse

Centre National De La Recherche Scientifique

Institut National De La Recherche Agronomique

Inserm (institut National De La Sante Et De La Recherche Medicale)

Philippe Valet

Cedric Dray

Claire Vinel

Francois Labaste

Bernard Frances

Vincent Minville

Magali Remaud-Simeon

Pierre Monsan

Bernard Malavaud

Rémy Burcelin

Oksana Kunduzova

Remy Burcelin

Jean-Sebastien Saulnier-Blache

Isabelle Castan-Laurell

Claude Knauf

Adrien Guerard

Victor Laurent

Catherine Muller

Pierre Gourdy

Laurent Cazals

Isabelle Laurell

François Labaste

Jean-Sébastien Saulnier-Blache

The present invention relates to methods and pharmaceutical compositions for the treatment of post-operative cognitive dysfunction. In particular, the present invention relates to a method of treating post-operative cognitive dysfunction in a subject in need thereof comprising administering to the subject a therapeutically effective amount of an APJ receptor agonist.

Methods and pharmaceutical compositions for the treatment of post-operative cognitive dysfunction

The present invention relates to an APJ receptor agonist for use in the treatment or the prevention of diabetes.

Method and pharmaceutical composition for use in the treatment of diabetes

The invention concerns an inhibitor of the expression of chemokine CCL7 or an inhibitor of the expression of the receptor CCR3 or an inhibitor of CCL7/CCR3 interaction for the use of same to prevent or treat the extension of prostate cancer outside the prostatic capsule in a subject. The invention also concerns a method for determining the degree of aggressiveness of a prostate cancer tumor in a subject suffering from prostate cancer, comprising a step of determining the concentration or level of expression of the receptor CCR3 in a sample of prostate tumor cells obtained from said subject.

Inhibition of chemokine CCL7 or receptor CCR3 of same for the treatment and diagnosis of prostate cancer

The present invention relates to an APJ receptor agonist or an apelinomimetic for use in the treatment or the prevention of a dysfunction associated with aging.

Pharmaceutical composition for use in the treatment of dysfunction associated with aging

The invention relates to the use of prebiotics for the preparation of food or pharmaceutical compositions which are intended for the treatment and/or prevention of hyperglycaemic syndromes and, in particular, for the treatment of Type II diabetes and/or the prevention of the onset of Type II diabetes in patients with a predisposition to developing the type of diabetes. The invention also relates to the food and pharmaceutical compositions containing the prebiotics.

Use of prebiotics, preferably glucooligosaccharide, for the prevention of the onset of type II diabetes

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Toulouse, France

Philippe Valet