Abivax

Centre National De La Recherche Scientifique

Universitè De Montpellier

Institut Curie

Deinove

Biokinesis

Artedrone

Pk Med

Carmat

Evexta Bio

Philippe Pouletty

Didier Scherrer

Hartmut Ehrlich

Sandrine Crabe

Jamal Tazi

Jean-Paul Leonetti

Jacques Biton

Antoine Capel

Frédérique Guillamot

Ivan Matic

Maëlle Bruneau

Clément Ducros

Jean-Claude Cadudal

The invention is directed to a method of determining properties in a vessel or the heart (V) of a patient. It comprises the steps of placing an element in a vessel or the heart(V) and determining a propulsion force () acting on the element. Furthermore, at least one of acceleration () and velocity () of the element is determined. At least one property of a neighbouring medium of the element is determined based on the propulsion force and at least one of acceleration () and velocity () of the element.

Method and system for determining properties in a vessel

A compound of Formula (I): or anyone of its metabolites or a pharmaceutically acceptable salt thereof, for use for treating and/or preventing an inflammatory disease, disorder or condition, wherein each R is independently hydrogen, halogen, —CN, hydroxyl, (C-C)fluoroalkyl, (C-C)fluoroalkoxy, (C-C)cycloalkyl, —NO, —NRR, (C-C)alkoxy, phenoxy, —NR—SO—NRR, —NR—SO—R1, —NR—C(═O)—R, —NR—C(═O)—NRR, —SO—NRR, —SOH, —O—SO—OR, —O—P(═O)—(OR)(OR), —O—CH—COOR, (C-C)alkyl; each R' is independently hydrogen, (C1-C3)alkyl, hydroxyl, halogen, —NO, —NRR, morpholinyl, morpholino, N-methylpiperazinyl, (C-C)fluoroalkyl, (C-C)alkoxy, —O—P(═O)—(OR)(OR), —CN, a —NH—SO—N(CH)group, or other groups and further relates to A compound of formula (IV): or a pharmaceutically acceptable salt thereof, for use for treating and/or preventing an inflammatory disease, disorder or condition, wherein V, Z, R, R', n, and n′ are as described above.

Quinoline derivatives for use in the treatment of inflammation diseases

The present invention relates to process for preparing a drug delivery composition comprising the steps of a) preparing a masterbatch comprising a drug and a first polymer by (i) extruding the first polymer, wherein said first polymer has a melting temperature below 140° C.; and (ii) introducing the drug during extrusion of the first polymer, with a drug content between 0.1% and 90%, based on the total weight of the masterbatch; and b) introducing the masterbatch in a polymer-based matrix during production of the drug delivery composition, wherein step a) is performed at a temperature at which the first polymer is in a partially or totally molten state, and step b) is performed at a temperature at which both the first polymer and at least a polymer of the polymer-based matrix are in a partially or totally molten state.

Process for preparing a drug delivery composition

An antitumor pharmaceutical combination includes (i) a compound ABX196 and (ii) at least one chemotherapeutic agent and/or at least one immunotherapeutic agent, for use in the treatment of cancer.

Combinations including ABX196 for the treatment of cancer

The compound ABX196 and pharmaceutical compositions including ABX196 are used in the treatment of bladder cancer.

ABX196 for use in the treatment of bladder cancer

The present invention relates to compounds of formula (I) and pharmaceutical compositions comprising such compounds, for use for treating and/or preventing endometriosis.

Derivatives of indole for the treatment of endometriosis

The present invention relates to composition and methods of producing bioenergy. More specifically, the invention relates to the use of bacterium of the genusand/or related genera for the modification of biomass or biomass derivatives with a view to producing bioenergy products and metabolites.

Use of bacteria for the production of bioenergy

Growing community of inventors

Paris, France

Philippe Pouletty