Sanofi-a Ventis Deutschland Gmbh

Sanofi-aventis Detuschland Gmbh

Philippe Nzike

Michael Schabbach

Michael Harms

Olaf Zeckai

Meinolf Werner

Steffen Raab

Uwe Dasbach

Uwe Boeser

Ole Simonowsky

Ulrich Brüggemann

Ulrich Bruggemann

Francisco Soares

Axel Roth

Christian Pommerau

Bernd Petermann

An assembly for a drug delivery device includes a housing, a rotation member, a drive member and at least one correction member. In a delivery mode, the drive member and the rotation member are coupled such that the drive member follows rotational movement of the rotation member in a first rotational direction. In a correction mode, the rotation member and the drive member are decoupled such that the rotation member is rotatable in the first rotational direction with respect to the drive member. For switching from the delivery mode into the correction mode, the correction member is moveable with respect to the housing, wherein the assembly is configured such that movement of the correction member with respect to the housing is converted into a relative movement between the drive member and the rotation member for decoupling the drive member and the rotation member.

Assembly for a drug delivery device and drug delivery device

The present disclosure is directed to a window element and a drug delivery device, like a pen-type injector, that provides for administration by injection of medicinal products from a multidose cartridge. The drug delivery device may comprise a housing, a dose setting member, a dial, a drive member, a clutch and/or a clicker. The window element comprises a first member with a window and being made from a rigid material, a second member and a third member, each made from an elastically deformable material and being attached to the first member.

Window element and drug delivery device

A peristaltic pump comprises a tube for transporting a material, wherein the tube is arranged linearly along a longitudinal axis. The peristaltic pump further comprises a pump head for causing a squeezing of the tube, wherein the pump head is rotatable about a rotation axis.

Peristaltic pump

A peristaltic pump comprises a tube to transport a material in a transport direction and one or more piezoelements, which are configured to cause a squeezing of the tube. Furthermore, a method of transporting material comprises the step of successively actuating the piezoelements along the transport direction of the material and thereby causing a squeezing of the tube.

Peristaltic pump and method of transporting material with a peristaltic pump

A cartridge holder () for retaining a cartridge () comprising a distal end and a proximal end being spaced apart from one another in the direction of an axis, an interior () which is suitable to receive and retain a cartridge () in a cartridge retaining section (B) of the interior (), and a main part () and at least one protrusion () which is moveably connected to the main part (). The protrusion () is arranged to define the radial extension of a subsection () of the interior (), wherein the subsection () is arranged at an axial position which is further away from the distal end than the cartridge retaining section (B). Furthermore, the protrusion () is arranged to vary the radial extension of the subsection () when the protrusion () is moved with respect to the main part (). Moreover, a method for securing a cartridge () in a cartridge holder () is proposed.

Cartridge holder and method for assembling a cartridge unit for a drug delivery device

The invention relates to a drive mechanism () for a needle insertion arrangement (), the drive mechanism () comprising a rotatable wheel () with a notch () having a closed curve geometry comprising a curved section () and a linear section (), wherein at least one cross beam () is movably arranged and engageable to an injection needle () to move it between a retracted position (RP) and an extended position (EP), wherein the cross beam () comprises a cam () adapted to engage the notch ().

Drive mechanism for a needle insertion arrangement

The invention relates to a drive mechanism () for a needle insertion arrangement (), the drive mechanism () including:&#x2014;a cross beam () linearly movable in a distal direction (D) and a proximal direction (P) for moving an injection needle (),&#x2014;an actuator (),&#x2014;a slider () coupled to the actuator () and linearly movable in a transversal direction (T) at right angles relative the distal direction D and the proximal direction D,&#x2014;a cam () on one of the cross beam () and the slider (),&#x2014;a guide track () in the other one of the cross beam () and the slider () adapted to engage the cam (), the guide track including a sloped section () such that the cross beam () is moved on movement of the slider ().

A peristaltic pump comprises a tube to transport a material in a transport direction and a conveying screw, which is configured to cause a transport of the material by causing a successive squeezing of the tube along the transport direction.

The invention relates to a drive mechanism () for a needle insertion arrangement (), the drive mechanism () comprising an actuator () coupled to a parallel linkage () adapted to convert a linear movement of the actuator () in a longitudinal direction (L) to a linear movement of a cross beam () in transverse direction (T) substantially at right angles with respect to the longitudinal direction (L).

The invention relates to a drive mechanism () for a needle insertion arrangement (), the drive mechanism () being arranged as a bistable mechanism with at least one pivoted link () having two stable end positions (LEP, UEP) and an instable transitional central position (CP), the drive mechanism () further comprising a spring () biasing the link () out of the transitional central position (CP), wherein at least one trigger unit () is arranged for moving the link () out of at least one of the stable end positions (LEP, UEP) towards and beyond the transitional central position (CP) against the bias of the spring ().

The invention relates to a drive mechanism () for a needle insertion arrangement (), the drive mechanism () comprising: &#x2014;an actuator (), &#x2014;a needle retainer () adapted to retain an injection needle () and linearly movable in a distal direction (D) and a proximal direction (P) for moving an injection needle (), &#x2014;a cam () arranged on or coupled to the needle retainer (), &#x2014;a guide curve () adapted to be rotated by the actuator () about an axis () aligned in the distal direction (D) and the proximal direction (P) and adapted to engage the cam (), wherein the guide curve () comprises a sloped section () such that the needle retainer () is moved on rotation of the guide curve ().

The invention relates to a drive mechanism for a needle insertion arrangement, the drive mechanism comprising: an actuator, a rotatable drive pulley directly or indirectly coupled to the actuator, and a belt adapted to engage the drive pulley and adapted to be fixed to a needle retainer.

Disclosed is a needle insertion arrangement () with a drive mechanism () comprising: a belt () frictionally engaging a first roller () and a needle retainer () with an injection needle () fixed to the belt, the first roller being rotatably arranged about an axis (A), a second roller () also rotatably arranged about the axis (A), a first spring () rotatably biasing the first roller against the second roller, a second spring () rotatably biasing the second roller against an arrester (), the first and the second roller being connected via an internal protrusion () and arcuate slot (), the two springs () biasing the rollers () from respective first to respective second angular positions (AP, AP, AP, AP), and a trigger mechanism () releasably locking the first and second rollers () such that upon pivoting the trigger button () in one direction, the first roller drives the belt in one direction to linearly transport the needle retainer towards an extended position, and upon pivoting the trigger button in the other direction, the first roller drives the belt back to retract the needle retainer.

Needle insertion and retraction arrangment with manually triggered, spring-loaded drive mechanism

A reservoir assembly comprising a reservoir housing, a piston, and a locking plug, both movably arranged inside the reservoir housing; wherein the volume between the piston and the locking plug defines a reservoir cavity. The reservoir assembly further comprising a reservoir outlet; and an actuator configured to act on the piston; wherein the locking plug is configured to be movable from a first position to a second position; wherein in the first position the reservoir outlet is not in fluid communication with the reservoir cavity. The reservoir assembly further comprising an interlock configured to prevent movement of at least one of the locking plug and the piston; wherein the interlock having a locked position and an unlocked position.

Needle assembly attachable to an injection device, the needle assembly having a reservoir assembly with locking mechanism

An assembly for a drug delivery device comprises a housing, a rotation member, a drive member and at least one correction member. The rotation member is adapted to be rotated with respect to the housing in a first rotational direction for delivering a dose of a drug. The drive member is coupleable to the rotation member for delivering the dose. In a delivery mode, the drive member and the rotation member are coupled such that the drive member follows rotational movement of the rotation member in the first rotational direction due to mechanical interaction of the rotation member and the drive member. In a correction mode, the rotation member and the drive member are decoupled such that the rotation member is rotatable in the first rotational direction with respect to the drive member.

Growing community of inventors

Frankfurt am Main, Germany

Philippe Nzike