Synthelabo

L'oreal

Philippe Michel Manoury

Henry Najer

Jean Louis Binet

Don Pierre Giudicelli

Daniel C Obitz

Gerard Defosse

Elisabeth Dewitte

Pascal George

Jean-Pierre Kaplan

Bernard M Raizon

Maurice Jalfre

Icilio A Cavero

Jean-Pierre Merly

Michel Peynot

Andre Pierre Dumas

Jean F Grollier

Jacques Froissant

Jonathan Reid Frost

Bogdan Iliesco-Branceni

Corinne Veronique

Alfred Saarmets

Mireille Sevrin

Guy Rossey

Benoit Marabout

David Machnik

Bernard Gaudilliere

Jean Rousseau

Regis Dupont

Arlette Tixidre

Gerard Cremer

Daniele De Peretti

Nigel R Beeley

Michel Mangane

Michael J Dimsdale

Michel Aletru

Najib Jabri

Jean Francedillaois Gibert

Jean-Marie Louis Roger

1-�2-(2,3-Dihydro-1H-inden-1-yl)ethyl!-4-(naphthalen-1-yl) piperazine,

Compounds corresponding to the general formula (I) ##STR1## in which n=2 or 3, X=H, F, Cl or OCH.sub.3, R=H or CH.sub.3, R.sub.1 =H or CH.sub.3, R.sub.2 =alkyl, hydroxyalkyl, (hydroxy)(methoxy)alkyl, dimethoxyalkyl, 2-(aminosulphonyl)ethyl, 2-(methylsulphonyl)ethyl, 2-(methylsulphonylamino)ethyl, aminocarbonylmethyl which is optionally substituted by nitrogen, phenylethyl which is optionally substituted, pyrimidinylaminoalkyl or arylcaronylaminoalkyl, or else R.sub.1 and R.sub.2 form, with the nitrogen which carries them, a piperidine, morpholine, thiomorpholine or piperazine ring, optionally substituted by nitrogen. Use in therapeutics.

2-aminopyrimidine-4-carboxamide derivatives, their preparation and their

A compound which is a 2-aminopyrimidine-4-carboxamide derivative represented by general formula (I) ##STR1## in which m represents 2 or 3,

2-aminopyrimidine-4-carboxamide derivatives, their preparaton and their

A compound of formula (I) ##STR1## in which n denotes 2, 3, 4, or 5,

2-Aminopyrimidine-4-carboxamide derivatives, their preparation and their

An indolone derivative is useful for the treatment of anxiety, depression and schizophrenia and is a 5HT.sub.1A agonist and 5HT.sub.2 antagonist, which is a compound of formula (I): ##STR1## in which R.sub.1 is a hydrogen or halogen atom or a (C.sub.1-4)alkyl radical,

Indolone derivatives, their preparation and their application in therapy

Phenyloxypropanolamine derivatives in the form of racemates or enantiometers, of formula (I) ##STR1## in which R is H or CH3, and their pharmaceutically acceptable salts.

Phenyloxypropanolamine derivatives and their application in therapeutics

A quinolinone derivative which is a compound of formula (I): ##STR1## in which: R.sub.1 and R.sub.2 are each, independently of one another, a hydrogen or halogen atom or a (C.sub.1-4)alkyl radical;

Quinolinone derivatives and their preparation in therapy

A piperazine derivative of formula (I) ##STR1## in which: R is hydrogen or a straight or branched (C.sub.1 -.sub.4) alkoxycarbonyl group; and

Piperazine derivatives and their preparation process

A pyrimidinedione derivative which is a compound of formula (I): ##STR1## in which: R1 denotes hydrogen, a halogen, a methyl group or a methoxy group,

6-phenyl-3-(piperazinyalalkyl)-2,4(1H,3H)-pyrimidinedione derivatives,

A compound which is a pyrimidinylamino derivative of piperidine of formula (I) ##STR1## in which: X is a (CH.sub.2).sub.2, CH.dbd.CH or CH.sub.2 --CO group;

1-1[(2-pyrimidinyl)amino-alkyl]piperidines, their preparation and their

New 1-piperazinylpyrimidine derivatives, preparation thereof and application thereof in therapeutics and cosmetics. New compounds derived from 1-piperazinylpyrimidine derivatives, and their application in therapeutics and cosmetics, corresponding to the general formula: ##STR1## in which R represents an alkoxycarbonyl group containing from 1 to 3 carbon atoms in the alkoxy chain or alternatively a furoyl group, n being 0 or 1, and their addition salts with cosmetically or pharmaceutically acceptable acids.

1-piperazinylpyrimidine compositions and application thereof in

Benzimidazole derivatives corresponding to the formula (I) ##STR1## in which X is CH or N,

2-[4-pyrimidin-2-yl amino)piperidin-1-yl]benzimidazole compound

1-((2-Pyrimidinyl)aminoalkyl)piperidines, their preparation and their

New compounds derived from 1-piperazinylpyrimidine derivatives, and their application in therapeutics and cosmetics, corresponding to the general formula: ##STR1## in which R represents an alkoxycarbonyl group containing from 1 to 3 carbon atoms in the alkoxy chain or alternatively a furoyl group, n being 0 or 1, and their addition salts with cosmetically or pharmaceutically acceptable acids.

1-piperazinylpyrimidine derivatives and application thereof in

A compound which is a benzimidazole derivative of formula (I) ##STR1## in which: R.sub.1 is hydrogen or methyl,

Antihistaminic benzimidazole derivatives

Growing community of inventors

L'Hay-les-Roses, France

Philippe Michel Manoury