UniversitÉde Strasbourg

Institut National De La Sante Et De La Recherche Medicale

Protip Medical

Centre National De La Recherche Scientifique

Institut National De La Sante Et De La Recherche Medicale (inserm)

Spartha Medical

Philippe Lavalle

Pierre Schaaf

Nihal Engin Vrana

Angela Mutschler

Fouzia Boulmedais

Nicolas Zydziak

Lorène Tallet

Cynthia Calligaro

Delphine Chan-Seng

Varvara Gribova

The present invention concerns a polymer comprising repetitive units having the following formula (I) wherein Ris H or Me; L is a linker; Ris the side chain of an &#x3b1;-amino acid being other than arginine; m is 0 or an integer comprised from 1 to 10; n is an integer comprised from 1 to 10; and X&#x2014; is a counterion.

Arginine-based antibacterial polymers with UCST property

The present invention concerns a polyelectrolyte coating comprising at least one polycationic layer consisting of at least one polycation consisting of n repetitive units having the formula (1) and at least one polyanionic layer consisting of hyaluronic acid. The polyelectrolyte coating has a biocidal activity and the invention thus further refers to the use of said polyelectrolyte coating for producing a device, in particular a bacteriostatic medical device, more particularly an implantable device, comprising said polyelectrolyte coating, and a method for preparing said device and a kit.

Crosslinkable polypeptide and hyaluronic acid coatings

Polypeptide and hyaluronic acid coatings

A polyelectrolyte coating comprises at least one polycationic layer consisting of at least one polyarginine as herein defined and at least one polyanionic layer consisting of hyaluronic acid. The polyelectrolyte coating has a biocidal activity and the invention thus further refers to the use of said polyelectrolyte coating for producing a device, in particular a bacteriostatic medical device, more particularly an implantable device, comprising said polyelectrolyte coating, and a method for preparing said device and a kit. Also disclosed is a method of preventing a bacterial infection in an individual.

Growing community of inventors

Wintzenheim, France

Philippe Lavalle