Institut Quimic De Sarria

Association Cardio-Monde

Universidad Politècnica De València

Creaspine

Fundacion Germans Trias Pujol

Fundacio Institut D'investigacio Sanitaria Germans Trias Pujol

Universitad Politecnica De Valencia

Fundacio Institut D'investigacio Sanitaria Germans Trias I Pujol

Philippe Jenny

Juan Carlos Chachques

Carlos Eduardo Semino

Antonio Bayes Genis

Manuel Monleon Pradas

Jean-Charles Lehuec

Nicole Zur Nieden

Marc Bernard

Bioactive implant for myocardial regeneration and ventricular chamber support including an elastomeric microporous membrane. The elastomeric microporous membrane being at least one non-degradable polymer and at least one partially degradable polymer. The non-degradable polymer is selected from polyethylacrylate and polyethylacrylate copolymerized with a hydroxyethylacrylate comonomer. The partially degradable polymer is selected from caprolactone 2-(methacryloyloxy)ethyl ester and caprolactone 2-(methacryloyloxy)ethyl ester copolymerized with ethylacrylate. The elastomeric microporous membrane further includes a nanofiber hydrogel, and cells. The bioactive implant, having one or two helical loops, contributes to the restoration of the heart conical shape. Cardiac wrapping by ventricular support bioprostheses of the present invention, having reinforcement bands spatially distributed as helicoids, recovers the sequential contraction of the myocardium resulting in the successive shortening and lengthening of the ventricles, therefore improving the ejection (systolic function) and suction of blood (diastolic function).

Bioactive implant for myocardial regeneration and ventricular chamber restoration

Bioactive implant for myocardial regeneration and ventricular chamber support including an elastomeric microporous membrane. The elastomeric microporous membrane being at least one non-degradable polymer and at least one partially degradable polymer. The non-degradable polymer is selected from polyethylacrylate and polyethylacrylate copolymerized with a hydroxyethylacrylate comonomer. The partially degradable polymer is selected from caprolactone 2-(methacryloyloxy)ethyl ester and caprolactone 2-(methacryloyloxy)ethyl ester copolymerized with ethylacrylate. The elastomeric microporous membrane further includes a nanofiber hydrogel, and cells. The bioactive implant, having one or two helical loops, contributes to the restauration of the heart conical shape. Cardiac wrapping by ventricular support bioprostheses of the present invention, having reinforcement bands spatially distributed as helicoids, recovers the sequential contraction of the myocardium resulting in the successive shortening and lengthening of the ventricles, therefore improving the ejection (systolic function) and suction of blood (diastolic function).

This implant () for osseous fusion is intended to be inserted between two adjacent vertebral bodies () of a spinal column. It comprises a main body () having at least two longitudinal elements of C-shaped contour () placed back to back and defining:&#x2014;a solid axis (), formed by the junction zone of said elements () and suitable for being positioned parallel to the spinal column and for transmitting the stresses between the two adjacent vertebral bodies, and&#x2014;at least two longitudinal apertures (), suitable for holding grafts, oriented outward with respect to said solid axis ().

Intervertebral implant intended for osseous fusion

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Pessac, France

Philippe Jenny