Centre National De La Recherche Scientifique

Biomerieux, Inc.

Université Claude Bernard Lyon I

Philippe Dugourd

Jean-Philippe Charrier

Tanguy Fortin

Arnaud Salvador

Jérôme Lemoine

Jéröme Lemoine

A method for detecting at least one target molecule in a sample by mass spectrometry, comprising ionizing the molecules of the sample and then conducting the following steps (i) and (ii) n times, n being equal to 0, 1, 2, 3 or 4: (i) at least one ion obtained in the preceding step is selected, according to the target molecule, in a mass analyzer, and (ii) the ion thus selected is fragmented in a fragmentation cell; trapping at least two different sampled ions, when n is zero, or when n is other than zero, in a mass analyzer, the at least two ions thus trapped having a mass-to-charge ratio m/z characteristic of the target molecule; ejecting the trapped ions from the mass analyzer; and detecting the ejected ions ejected by means of a detection device. The method is characterized in that the characteristic ions are ejected simultaneously and detected simultaneously.

Method for detecting molecules through mass spectrometry

Growing community of inventors

Dardilly, France

Philippe Dugourd