Université Joseph Fourier

Université Grenoble Alpes

Centre Hospitalier Universitaire Grenoble Alpes

Centre National De La Recherche Scientifique

Institut National De La Sante Et De La Recherche Medicale

Aesculap Ag & Co Kg

Université Joseph Fourier - Grenoble 1

Surgiqual Institute

Other

Institut National Polytechnique De Grenoble

Institut National Des Sciences Appliquees De Toulouse

Uromems

Centre Hospitalier Universitaire De Grenoble

Institut National De La Sante Et De La Recherche Medicale (inserm)

Perception Raisonnement Action En Medecine

Philippe Cinquin

Donald Keith Martin

Stephane Lavallee

Jocelyne Troccaz

Abdelkader Zebda

Jean-Pierre Alcaraz

Laurent Desbat

Francois Leitner

Dominique Saragaglia

Frederic Picard

Hans-Joachim Schulz

Jacques Thelu

Pierre Mozer

Serge Cosnier

Richard Laurent Minfelde

Jean Arnault

Denis Favier

Sandrine Voros

Philippe Augerat

Yannick Grondin

Aziz Bakri

François Lenouvel

Alain Jacquet

Vanessa Durrieu

Chantal Gondran

Sarra El Ichi

Patrick Tuvignon

Olivier Cinquin

Nawel Khalef

Peter Berkelman

Stéphane Lavallee

Hamid Lamraoui

Alexandre Moreau-Gaudry

Bertrand Toussaint

Pierre-Yves Gumery

Naceur Belgacem

Agnes Bonvilain

Audrey Le Gouellec

Fabien Giroud

Aurel Messas

Stéphane Mathe

Jean-Alexandre Long

Thierry Alonso

Gilberte Robain

Donald Martin

Dominique Schneider

Juan Carlos Avila Vilchis

Adriana Herlinda Vilchis Gonzalez

Georges Bettega

Bruno Mazier

Jean-Marc Kweter

Sylvain Besson

Olivier Peria

Lionel Brunie

Francis Dubois

Thomas Soranzo

Guillaume Champlebaux

Eric Bainville

Remi Julliard

Aymeric Pellissier

Bernard Raphael

Fabian Reche

Angel Mariano Cruz Abud

Max Maurin

Benjamin Spencer

Marion Decrouez

Pierren Mozer

Christophe Marmignon

Laurent Orgeas

Matthieu Pecher

Sonia Pujol

Richard Minfelde

St&eacute;phane LaVallee

Pascal Defaye

Donald K Martin

François Régis Pierre Boucher

The application relates to a device for collecting a sample of intestinal fluid comprising a polymeric inner material having an at least partially compressed open cell structure, having a volume Vand being suitable for swelling to a volume greater than or equal to 1.1×Vby absorbing intestinal fluid, said material being encased with an elastic polymeric casing impervious to digestive fluid, said casing comprising at least one opening allowing the intake of intestinal fluid into the inner material, a gastro-resistant material suitable for dissolving in intestinal fluid at 37° C. being disposed on top of each opening, and at least one mechanism for closing the opening(s).

Device for collecting intestinal fluid

A capsule configured for collecting samples in the intestine, comprising a body delimiting at least one compartment for receiving samples and comprising at least one opening for samples intake, and a mobile mechanism for opening and/or closing the opening controlled by the dissolution of a material which is dissolvable in the intestine.

Device for taking an intestinal sample

A device intended to be implanted in a human or animal body, in order to produce hydrogen in situ from molecules present in the body medium in which the device is implanted, this device having an anode and a cathode, which are each electrically connected to a pole of an electrical energy source, and having a semi-permeable material separating the electrodes from the body medium, in which device, when the connection to the electrical energy source is effective in situ, in the presence of body fluid, a closed electrical circuit is formed, with production of hydrogen at the cathode, the semi-permeable material having a cutoff threshold of between 50 and 500 Da.

Implantable device for producing hydrogen

Thermo-electric generator which is intended to be immersed in a fluid which contains at least one chemical species, comprising two electrodes each having a first end and a second end, the first ends being connected to each other, the generator being configured to generate an electrical voltage between the two ends when a temperature difference is imposed between each first end and the corresponding second end, the temperature difference being such that one end, referred to as the 'hot end', of each electrode has a temperature which is strictly greater than the temperature of the other end. The hot end of at least one electrode comprises a micro-organism or an enzyme which is capable of causing at least one exothermic reaction involving the chemical species.

Thermo-electric generator, associated implantable device and method

The invention relates to an implantable device suitable for being fixed in a fixation position to a wall of a patient's stomach, the implantable device being accommodated in the stomach when the implantable device is in the fixation position, the implantable device being characterised in that it comprises a reserve of an active substance and an injector suitable for administering the active substance to the patient.

Implantable device

The device, that can be implanted in the intestinal cavity, comprises a reactor comprising a semi-permeable or porous membrane or coating linked to a element for attachment to an intestinal or gastric wall. The reactor can be in the form of a ribbon, a structure having more than two faces or an open structure delimiting a lumen, comprising, or formed from, a semi-permeable or porous membrane. The reactor can also delimit, at least partially with the semi-permeable or porous membrane of same, a closed inner space. The reactor can comprise or carry enzymes or micro-organisms, in particular bacteria or yeast. The reactor is used for generating a chemical reaction with one or more molecules present in the intestine, or for producing one or more biologically active molecules. It can, in particular, be used for consuming sugars, disaccharides and simple sugars or producing essential amino acids or other molecules having a positive effect on the health.

Implantable intestinal reactor

A device positions and/or orients in the body of a patient, a surgical tool carried by a tool-holder, including a platform capable of being placed on the body of the patient, an orientable carrier, at least one part of which is rigidly connected to the tool-holder, means for guiding the orientable carrier rotationally relative to the platform in two directions of a plane parallel to the platform, at least 2 pneumatic actuators which engage with the orientable carrier such that a variation in pressure of at least one of the pneumatic actuators causes the orientable carrier to rotate in the first direction and/or the second direction, in which the pneumatic actuators are volumes that can deform in a predetermined direction as a function of the internal pressure.

Device for positioning a surgical tool in the body of a patient

Radiographic imaging system including: an x-ray transmission unit; an x-ray receiver unit; a plate made from a material opaque to x-rays and situated between the transmission unit and the receiver unit, the plate including at least four channels, each channel enabling a part of the x-rays emitted by the transmission unit to pass through the channel; and an image processing unit configured to determine the coordinates of the projected patterns and to calculate a position of the receiver unit from the coordinates of the projected patterns and from the coordinates of the channels.

Radiographic imaging system and method for positioning one such system

The invention relates to an X-ray imaging device including a rotary collimator having a region () which is opaque to X-rays, a first slot () and a second slot (), which are transparent to X-rays and extend in two different directions, passing through the opaque region, the collimator making it possible to determine the position of an element provided with X-ray sensors in an imaging system (FIG.).

Rotary collimator for determining the position of an element provided with sensors in an X-ray imaging system

The invention concerns a device to prevent urinary leakage intended to be implanted in a patient, comprising:

Device to prevent urinary leakage

The invention concerns a bioreactor obtained by compressing a mixture of an enzyme, a conductor and chitosan. The conductor can consist of carbon nanotubes. This bioreactor can be produced according to the following steps: preparing a mixture of powders in which the proportion of enzyme powder relative to a carbon nanotube powder is of the order of 50/50 by weight; preparing a viscous solution of chitosan in a ratio of 5 to 15 (in mg) of chitosan to 0.75 to 1.25 (in ml) of acetic acid diluted to 0.4 to 0.6% by volume in water; adding the viscous chitosan to the mixture of powders in a proportion be weight of 3 to 5 of powder to 5 to 10 of chitosan; carrying out a first compression followed by light grinding; carrying out a second compression to produce a pellet; and drying at ambient temperature.

Implantable biocompatible reactor

The invention concerns an analysis method for a surgical operation via endoscopy performed at an operative site in a volume located inside the body of an animal, characterized in that it comprises the steps consisting of:

System and method for analysing a surgical operation by endoscopy

The present invention relates to a system for positioning with respect to a patient's body an observation and/or intervention device having a portion penetrating into the patient's body comprising a base disposed over the patient's body; a means for supporting the device formed of a first portion movably assembled on the base according to a connection with one degree of freedom, and of a second portion movably assembled on the first portion according to a connection with one degree of freedom and connected to the device; and means for actuating the first portion with respect to the base, and the second portion with respect to the first portion, in which the base surrounds at a distance at least partially the device, said device being detachably connected to the second portion to enable removal of the positioning system while leaving in place the device.

System for positioning on a patient an observation and/or intervention device

The invention relates to a device comprising a casing and a biomimetic artificial membrane arranged within the casing to form two distinct chambers, wherein each chamber is provided for enclosing a liquid of a given composition, and wherein the biomimetic artificial membrane comprises a semi-permeable membrane for supporting a lipid membrane, the lipid membrane comprising a plurality of lipid molecules arranged in a layer and including at least a transport protein, the transport protein being adapted for transport of ions and/or molecules of the liquids between the two chambers.

Biomimetic artificial membrane device

The invention relates to a device () for changing the pH of a solvent in which a substance is dissolved. The device includes a housing () in contact with the solvent through a housing wall () that is permissive to the solvent and the substance. The housing contains enzymes adapted for converting the substance in order to provide hydrogen or hydroxyle ions; the housing wall being non-permissive to the enzymes.

Method and device for changing the pH of a solution

Growing community of inventors

Saint Nazaire les Eymes, France

Philippe Cinquin