Institut National De La Sante Et De La Recherche Medicale

Universitè De Montpellier

Centre Hospitalier Universitaire De Montpellier

Université D'auvergne

Centre National De La Recherche Scientifique

Ecole Nationale Superieure De Chimie

Université Clermont Auvergne

Philippe Brabet

Thierry Durand

Céline Crauste

Joseph Vercauteren

Christian Hamel

David Cia

Laurent Guillou

Claire Vigor

Espérance Moine

The invention relates to compound of formula (I): in particular flavonoid derivatives (quercetin and catechin derivatives), for use in the prevention and/or the treatment of a disease or disorder involving both carbonyl and oxidative stresses.

Lipophenolic flavonoid derivatives useful to reduce carbonyl and oxidative stresses (COS)

The present invention relates to a compound of formula (I) wherein: i is 0 or 1; j is 0 or 1; k is 0 or 1; Rand Rare in particular H, (C-C)alkyl, or a group of formula C(O)R; R is a, linear or branched, alkyl radical, comprising at least 19 carbon atoms; Ris H and k=0 when j=1; or, when j=0, Ris &#x2014;C(O)R or -L-C(O)R; L, U and L&#x2033; are linkers; wherein, when j=0, at least one of the groups R; Rand Rcomprises a radical R. 

Lipophenol compounds and uses thereof

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Montpellier, France

Philippe Brabet