Other

Astrazeneca Ab

Ingenium Pharmaceuticals Gmbh

Biotropics Malaysia Berhad

Neem Biotech Limited

Rahn Ag

Grothe, Torsten

Stadler, Marc

Philipp Wabnitz

Michael A Pleiss

Martin Augustin

Hans Allgeier

Jens Bitzer

Gabriele Stumm

Thomas Küper

Torsten Grothe

Matthias Gehling

Bärbel Köpcke

Marc Stadler

Ernst Roemer

Gisela Peraus

Anke Mueller

Joelle Le

Jackie Macritchie

Don Simpson

Gerhard Mueller

Rozita Zamri

Annie George VK George

The invention relates to compositions and methods (with regard to animals and humans) for utilizing an extract and/or one or more natural spiro triterpenoids and derivatives thereof alone or as a supplement. Certain materials utilized are from the blazeispirol family, obtainable fromspecies. Treatments include the prophylactic and/or therapeutic treatment of a disease, disorder or condition that responds to the modulation of Liver X receptor, as well as corresponding methods of treatment, the manufacture of a pharmaceutical and nutraceutical formulation for said treatment. The invention also relates to the use of the extract and compound(s) in the treatment or in the preparation of a medicament (e.g. a nutraceutical) for the prophylactic and/or therapeutic treatments, as well as their preparation. It also relates to pharmaceutical or nutraceutical formulations described herein which are useful in prophylactic and therapeutic treatments. They can also be used for non-therapeutic, e.g. cosmetic, purposes.

Terpenoid spiro ketal compounds with LXR agonists activity, their use and formulations with them

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Düsseldorf, Germany

Philipp Wabnitz