Receptos, Inc.

Philip Turnbull

Adam Richard Yeager

Junko Tamiya

Liming Huang

Lin Zhang

Thomas Fowler

Marcos Steinberg

Roger Bakale

Junhua Fan

Tom Fowler

Greg P Iacobini

Matthew Richard Crittall

Craig Grant

Raffaele Pasceri

Brahmachary Enugurthi

Andrew Robbins

Hanae Benelkebir

Maria Ieva

Kevan Grant

Ephraim Vidal

David Moser

Yang Tran

Compounds are provided that modulate the glucagon-like peptide 1 (GLP-1) receptor, as well as products containing such compounds, and methods of their use and synthesis. Such compounds have the structure of Formula (I) below: (I) or pharmaceutically acceptable salts thereof, wherein A, J, W, Y, Z, R, R, Rand Rare as defined herein. 

GLP-1 receptor modulators

Crystalline 2-hydroxy-N,N-dimethylethanaminium 1-(2-(5-(tert-butyl)-thiophene-2-carboxamido)-3-(4-(5-(4'-ethyl-[1,1&#x2032;-bi(cyclohexan)]-3-en-4-yl)pyrimidin-2-yl)phenyl)propanoyl)azetidine-3-carboxylate salt, and methods related to synthesis and therapeutic use of the same.

Dimethylaminoethanol salt of a GLP-1 receptor modulator

Compounds are provided having the structure of the following Formula I: where R, R, R, Rand Rare as defined herein. Pharmaceutical compositions comprising such compounds, as well as methods related to their manufacture and use, are also provided.

CXCR3 receptor agonists

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San Diego, CA, United States of America

Philip Turnbull