Dyadic International (usa), Inc.

Other

Dyadic International, Inc.

Philip Terry Olson

Arkady Panteleimonovich Sinitsyn

Mark Aaron Emalfarb

Richard Paul Burlingame

Peter Jan Punt

Christine Marie Pynnonen

Jean Christophe Bousson

Martine Parriche

Cornelia Marie Johanna Van Zeijl

Arie Ben-Bassat

Irina Vladimirovna Solovjeva

Vladimir Mikhaylovich Chernoglazov

Richard P Burlingame

Cornelia Maria Johanna Van Zeijl

Oleg Nicolaevich Okounev

Oleg Nicolaevich Ocounev

Mark Aaron Emalfrab

Cornelia Maria Van Zeijl

A novel transformation system in the field of filamentous fungal hosts for expressing and secreting heterologous proteins or polypeptides is described. The invention also covers a process for producing large amounts of polypeptide or protein in an economical manner. The system comprises a transformed or transfected fungal strain of the genus, more particularly ofand mutants or derivatives thereof. It also covers transformants containingcoding sequences, as well expression-regulating sequences ofgenes. Also provided are novel fungal enzymes and their encoding sequences and expression-regulating sequences.

Transformation system in the field of filamentous fungal hosts

A computer-based method and apparatus for the analysis specification and support of work processes. The system is designed to support multiple interdependent decisions, at least some of which require collaboration among multiple participants (). Work processes are modeled using an application framework () used to develop abstract, decision () process models. The decision () process models are used as a pattern to instantiate concrete process models that incorporate the work defined by the abstract process. The process model is then used to instantiate project models that incorporate the required work from the process. The project models are used to direct and guide the behavior of the participants () in the work process.

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A novel transformation system in the field of filamentous fungal hosts for expressing and secreting heterologous proteins or polypeptides is described. The invention also covers a process for producing large amounts of polypeptide or protein in an economical manner. The system comprises a transformed or transfected fungal strain of the genus Chrysosporium, more particularly of and mutants or derivatives thereof. It also covers transformants containing Chrysosporium coding sequences, as well expression-regulating sequences of Chrysosporium genes. Also provided are novel fungal enzymes and their encoding sequences and expression-regulating sequences.

The subject invention relates to novel compositions of neutral and/or alkaline cellulase and methods for obtaining neutral and/or alkaline cellulase compositions from Chrysosporium cultures, in particular Chrysosporium lucknowense. This invention also provides mutants and methods of generating mutants of Chrysosporium capable of producing neutral and/or alkaline cellulose. This invention also relates to the genes encoding the enzymes comprising the neutral and/or alkaline cellulase composition. In addition, this invention provides methods of culturing Chrysosporium to produce neutral and/or alkaline cellulases. The neutral and/or alkaline cellulase compositions of the subject invention can be used in a variety of processes including stone washing of clothing, detergent processes, deinking and biobleaching of paper & pulp and treatment of waste streams.

Cellulase compositions and methods of use

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Manitowoc, WI, United States of America

Philip Terry Olson