Tandem Diabetes Care, Inc.

Thync, Inc.

Cardionet, Inc.

Cerevast Medical, Inc.

Philip S Lamb

Michael Michaud

Isy Goldwasser

Daniel Z Wetmore

William J Tyler

Steven B Cook

Sumon K Pal

Jonathan D Charlesworth

Raymond Louis Gradwohl

Remi Demers

Justin Brown

Christopher Voss

Geoffrey A Kruse

Robert Eastridge

Ryan William Betts

Michael Fitzgibbons

Sean T Saint

Michael J Rosinko

Lon M Severe

John Charles Nadworny

Tomokazu Sato

William T Trevaskis

Donald Ludolph

Anthony Barghini

Marcus Julian

Maxwell Aaron Hume

Steven Thuan Truong

Alexander Seitz

Han-Ting Chang

Caleb Butler

Larry Dube

Alexander Opitz

Laurent F Dube

Jonathan Charlesworth

Raymond L Gradwohl

A user-wearable patch pump system for delivery of insulin or other medicament can include a pump and an attachment portion that attaches the pump to a user's body. The pump can include a drive unit and a disposable cartridge containing a medicament with the drive unit configured to cause the pump to deliver the medicament in the cartridge to the user. The attachment portion can include a retention frame configured to selectively retain the pump therein and an adhesive patch configured to be attached to the user's body. The pump can be selectively attached to the retention frame and used to deliver medicament either through a cannula to an infusion site directly beneath the retention frame or through tubing to an infusion site displaced from the retention frame.

Insulin patch pump

A user-wearable patch pump system for delivery of insulin or other medicament can include a patch pump having a reusable drive unit and a replaceable and refillable cartridge. The cartridge can selectively attach to and be detached from the drive unit. The cartridge can initially be inserted onto the drive unit in a first orientation at an angle to the drive unit and then be rotated to align the cartridge with the drive unit and lock the cartridge in place on the drive unit to form the patch pump.

Patch pump cartridge attachment

Disclosed herein are systems and methods for monitoring performance of an ambulatory infusion pump. An ambulatory infusion pump can include a reservoir configured to contain a medicament including a plunger at a proximal end of the reservoir and an outlet port at a distal end of the reservoir. A motor can be configured to cause linear motion of a pushrod to contact and move the plunger to cause medicament to flow from the reservoir out of the outlet port to a patient. An optical encoder can be employed to monitor a linear position of the pushrod. In addition, the optical encoder can be employed to monitor additional system conditions and/or a secondary encoder can be employed to monitor the performance of the optical encoder.

Methods and systems for detecting infusion pump conditions

Devices and methods for filling a medicament cartridge of a pump, including a user-wearable, ambulatory infusion pump. A device for supporting a medicament cartridge can comprise a body portion resembling a tray, with recesses disposed therein to support one or more of a cartridge body, cartridge tubing, interconnect fitting, and vial adapter. The recesses of the tray may be shaped to correspond to that component intended to be placed in its respective recess so to provide a visual indication to a user how to couple and align the various components necessary to fill the cartridge.

Vial supporter for medicament pump

Methods and systems are disclosed wherein temperature in a device such as an ambulatory infusion pump is monitored during inductive charging of the device such that temperature-sensitive contents or components, such as, for example, insulin, particular circuitry and/or other components are not damaged. Temperature can be monitored in the device at one or more locations during inductive charging. If the temperature breaches one or more predetermined thresholds and/or is rising at a rate greater than one or more predetermined thresholds, charging can be suspended or provided at reduced power to prevent the temperature from further rising and damaging the contents and/or components of the device. One or more alerts associated with these events may also be triggered so that the user is aware of the situation and may take corrective action.

System and method for inductively charging a medical device

User-wearable holder for medical device

Methods and systems for coupling ultrasound to the body, including to the head, are disclosed. The system is optionally configured to transmit ultrasound energy for transcranial ultrasound neuromodulation. Couplant assemblies are described that incorporate a semi-solid component that interfaces directly to the user's body and face of the ultrasound transducer. These couplant assemblies can be shaped, molded, or otherwise machined and, in some embodiments, contain one or more liquid, gel, or other non-solid component in an enclosed reservoir of the couplant assembly. Beneficial embodiments of ultrasound coupling assemblies described herein include those that conform to the contour of the user's body (e.g. the user's head for transcranial applications) and can easily be removed without leaving a messy residue. By having solid materials physically contacting the body, no residue is left that requires cleanup.

Systems and devices for coupling ultrasound energy to a body

A user-wearable patch pump system for delivery of insulin or other medicament can include a pump and an attachment portion that attaches the pump to a user's body. The pump can include a drive unit and a disposable cartridge containing a medicament with the drive unit configured to cause the pump to deliver the medicament in the cartridge to the user. The attachment portion can include a retention frame configured to selectively retain the pump therein and an adhesive patch configured to be attached to the user's body. The pump can be selectively attached to the retention frame and used to deliver medicament through tubing to an infusion site displaced from the pump.

A portable medical device includes an interface for accepting a power supply and enabling data transfer while still connected to a human body. The interface may include a universal serial bus interface and may be coupled to a data isolation chip and a power isolation chip. A power controlling processor may determine how the supplied power, e.g., voltage, is supplied to other components within the infusion device. Additional circuitry within the system may provide a secure power transfer within the device to ensure user safety and ensure that a high frequency noise is properly attenuated.

Sealed infusion device with electrical connector port

Growing community of inventors

San Diego, CA, United States of America

Philip S Lamb