The Royal Institution for the Advancement of Learning / Mcgill University

Other

Philip Roche

Mark Trifiro

Miltiadis Paliouras

Lenore Beitel

Vamsy Chodavarapu

Andrew Kirk

Mohamed Najih

Joachim Thiemann

Idit Dotan

Carlos Alvarado

Matthew Carnevale

Elliot Jonathan Mitmaker

A heating mechanism for use in DNA applications such as DNA amplification, extraction and sterilization is provided. Nanoparticles having photo-thermal properties are put in contact with a reaction mixture and irradiated with an activation light beam to activate these photo-thermal properties, thereby releasing heat. Nanoparticles of several types may be used. Use of the same nanoparticles or of different one to monitor the reaction using a different light beam is also presented.

Heating mechanism for DNA amplification, extraction or sterilization using photo-thermal nanoparticles

A bionanofluid includes a carbon-based nanomaterial substantially mono-dispersed in a fluid. The carbon-based nanomaterial is surface modified with a polar group when the fluid is polar or with a non-polar group when the fluid is non-polar, and functionalized with a biological targeting moiety to allow specific association of the carbon-based nanomaterial to a targeted entity. A hybrid bionanofluid includes the bionanofluid, with the carbon-based nanomaterial further modified with a hybrid nanoparticle which includes an alloy, transition metal, semi-conductor, semi-metal or polymer based nanoparticle with biological targeting moiety. A hydrogel, foam, cream, spray or dried product includes the bionanofluid or hybrid bionanofluid. The bionanofluid or hybrid bionanofluid are useful in multimodal imaging (photo-luminescence, luminescence, photo-acoustic, MRI, ultrasound) and/or cellular targeting.

Bionanofluid for use as a contrast, imaging, disinfecting and/or therapeutic agent

Growing community of inventors

Mount Royal, Canada

Philip Roche