E.i. Dupont De Nemours and Company

Philip Osborne Moss

Gary David Annis

Stephen Ernest Jacobson

Albert Loren Casalnuovo

Richard James Brown

The present invention pertains to methods for preparing a compound of Formula (I), wherein A is O or N-L; each L is independently H or an acyl group; K is, together with the two contiguous linking carbon atoms, a phenyl ring, a 5- or 6-membered heteroaromatic ring or an aromatic 8-, 9- or 10-membered fused carbobicyclic or heterobicyclic ring system wherein each ring or ring system is optionally substituted; Ris H, Cto Calkyl or COR; Ris H or Cto Calkyl; and Ris Cto Calkyl; comprising hydrogenating a compound of Formula (II), wherein n is 0, 1 or 2 in the presence of a catalyst comprising palladium to form the compound of Formula (I). This invention further pertains to methods for preparing compounds of Formula (II) useful for preparing compounds of Formula (I). This invention also pertains to compounds used in these methods 

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Wilmington, DE, United States of America

Philip Osborne Moss