Carnegie Mellon University

Lifeware Labs, LLC

Other

University of Pittsburgh

Agency for Science, Technology and Research

Philip LeDuc

Carmel Majidi

Alexandros Charalambides

Brian Stancil

Andrew Rape

Nolen Keeys

William Messner

Bin Li

Lee E Weiss

Gary Keith Fedder

Christopher J Bettinger

Chao-Min Cheng

O Burak Ozdoganlar

Jonathan Cagan

Naser Naserifar

Daniel Clymer

Yong-Tae Kim

George M Whitesides

Donald Elliot Ingber

Yadong Wang

Emanuele Ostuni

Shuichi Takayama

Zhou Yu

Mary E Wilson

Emrullah Korkmaz

Utku Sonmez

Liron Pantanowitz

Janet Catov

Yukai Zeng

Keng-Hwee Chiam

Matthew Brandon Kuczenski

Brandon Kuczenski

Yong Tae Kim

Donna Beer-Stolz

Keiji Naruse

A method of replicating master molds used in the fabrication of microsystems having micron to millimeter sized features. Master molds are replicated using a polymer sheet, which is heated and melted onto an elastomeric mold fabricated from the master mold. The copy molds accurately replicate the geometries of the master mold, such as high aspect ratio features, microposts, and channels with slender sidewalls. The polymer sheet encases the elastomeric mold without the application of an external force, permitting copying without deformation of the features.

Polycarbonate heat molding for soft lithography

An apparatus for communication, a system thereof, and methods of manufacture thereof are provided. The apparatus comprises a body and a printed circuit board (PCB) operatively coupled to the body. The PCB comprises a processing unit, a first communication module operatively coupled to the processing unit, and an array of assemblies. The first communication module is configured to communicate with a secondary communication module wirelessly. The array of assemblies comprises at least two rows and at least two columns. Each assembly comprises a switch and a light. The array of assemblies are operatively coupled to the processing unit. Each light is configured to change a state responsive to at least one of a change in state by the switch within the same assembly and a control signal from the first communication module.

Digital patch for discrete signaling, a baseball glove including same, and related method of manufacture

A flexible and stretchable integrated electronic device includes a substrate having a stiffness gradient, wherein a rigid electronic device is embedded within the substrate. The stiffness gradient within the substrate prevents delamination at the interface between the substrate and the embedded device. The stiffness gradient is accomplished by providing at least two distinct zones in the substrate with uniform stiffness, with each zone decreasing in stiffness as in a distance from the embedded device increases, or the gradient is accomplished by having a zone with a varying stiffness.

Integrated electronic device with flexible and stretchable substrate

A hierarchical deep-learning object detection framework provides a method for identifying objects of interest in high-resolution, high pixel count images, wherein the objects of interest comprise a relatively a small pixel count when compared to the overall image. The method uses first deep-learning model to analyze the high pixel count images, in whole or as a patchwork, at a lower resolution to identify objects, and a second deep-learning model to analyze the objects at a higher resolution to classify the objects.

Method for object detection using hierarchical deep learning

A method and device for fabricating vascular networks in for tissue engineering. The vascular network is embedded in a porous scaffold and is created from a sacrificial wax template, according to one embodiment. A extrusion-based three dimensional printer is used to create the template, wherein the printer utilizes an extruder incorporating a mixer to maintain the consistency of the extrudate.

Method and device for producing vasculature through extrusion-based 3D printing

The present invention relates generally to a method that is used to create three-dimensional synthetic vascular networks. Micromachining and molding techniques are used to create a template in a shape that mimics a biological network. Cellular material can be seeded around the template or a space created by the template and grown into an engineered tissue-construct.

Method for engineering three-dimensional synthetic vascular networks through mechanical micromachining and mutable polymer micromolding

A flexible and stretchable integrated electronic device comprising a substrate having a stiffness gradient, wherein a rigid electronic device is embedded within the substrate. The stiffness gradient within the substrate prevents delamination at the interface between the substrate and the embedded device. A method of fabricating an integrated electronic device having a stiffness gradient comprises applying a curing agent to an uncured polymer base material.

This invention provides an apparatus and method for culturing cells to probe the influence that the properties of a surface onto which the cells are bonded has on the properties of the cell.

Methods, apparatuses, and systems for cell and tissue culture

A fluid-pressure regulator for regulating the pressure of a fluid. The regulator includes a variable-resistance fluid element and a variable-volume fluid element located downstream of the variable-resistance element. Pressure in the fluid at the outlet of the regulator is controlled by substantially simultaneously changing the resistance of the variable-resistance element and the volume of the variable-volume element. In one example, a decrease in pressure is effected at the outlet by simultaneously increasing the resistance of the variable-resistance element and increasing the volume of the variable-volume element. Some embodiments of the regulator are particularly useful to effect long-term and high-speed pressure changes in high-resistance fluidic channel networks.

Fluid-pressure regulation systems and software

Fluid-pressure regulator and related methods and systems

A method of optical fabrication comprises coating a substrate with a photocuring material, controlling the application of light to the photocuring material so as to control the intensity and pattern of the light both in-plane and out of plane, and developing the photocuring material.

Method of optical fabrication of three-dimensional polymeric structures with out of plane profile control

Growing community of inventors

Pittsburgh, PA, United States of America

Philip LeDuc