Drexel University

Temple University

Philip Lazarovici

Peter I Lelkes

Mengyan Li

Yah-El H Har-el

Jonathan A Gerstenhaber

Sogol Moaiyed Baharlou

Cezary Marcinkiewicz

Anat Perets

Honesto Poblete

Jonathon A Gerstenhaber

Compositions and methods for the promotion of wound healing and tissue regeneration are described. The compositions and methods make use of water-soluble soy protein isolates (WSsoy), Fraction 5, Fraction 9, and/or bioactive peptide components of soy protein isolates. The invention also relates to the unexpected discovery that purified WSsoy forms gel-like matrices when suspended within certain concentration ranges in an aqueous environment. The compositions of the invention comprising WSsoy promote natural healing and have a low risk profile.

Soy-derived bioactive peptides for use in compositions and methods for wound healing, tissue engineering, and regenerative medicine

Methods of making a biologically active three-dimensional scaffold capable of supporting growth and differentiation of a cell are described. Biologically active three-dimensional scaffold made by the methods of the invention and an engineered tissue made from the scaffolds are described. Fibers of desired porosity can be obtained from non-structural ECM by lyophilization and/or electrospinning which can be useful for numerous tissue engineering applications requiring complex scaffolds, such as wound healing, artificial skin (burns), soft tissue replacement/repair and spinal cord injury.

Three-dimensional scaffolds for tissue engineering made by processing complex extracts of natural extracellular matrices

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Jerusalem, Israel

Philip Lazarovici