Adir Et Compagnie

Philip Janiak

Jean-Paul Vilaine

Jean-Louis Peglion

Nicole Villeneuve

Christophe Thurieau

Joel Vian

Jean-Luc Fauchere

Jean-Pierre Bidouard

The invention relates to a compound selected from those of formula (I) (SEQ ID NO:1): ##STR1## in which R.sub.1, R.sub.2, X.sub.1 and X.sub.2 are as defined in the description, useful as inhibitor of the proliferation component of vascular smooth muscle cells.

Angiopeptin cyclopeptide compounds

Compounds of formula (I): ##STR1## wherein R.sub.1, R.sub.2, U, X, Y, Z, n, m, p and r are as defined in the description, and medicaments containing the same.

N-(isoquinolin-5-ylsulphonyl) azacycloalkanes

The compounds are 3-[ (benzocycloalkyl)alkyl amino alkyl] -1,3,4,5-te trahydro 2H- 3-benzazepin-2 ones useful in cardiovascular field. A compound disclosed is (R,S)-7,8-dimethoxy-3-{3-{N-[(4,5-dimethoxybenzocyclobut-1-yl) methyl]-N-methyl amino}propyl}-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one.

(Benzocycloalkyl) alkylamines

Compounds of formula (I): ##STR1## with R.sub.1, R.sub.2, U, X, Y, Z, n, m, p and r as defined in the description. Medicinal products.

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Clichy, France

Philip Janiak