Boston Biomedical Research Institute

The General Hospital Corporation

Massachusetts General Hospital Corporation

Philip J Graceffa

Sigmund A Weitzman

This invention pertains to an improved method of inhibiting peroxide-reduction catalytic activity and concomitant toxicity of asbestos and nonasbestos iron-containing silicates. These undesirable reactions can be substantially reduced or essentially eliminated by contacting these potentially harmful materials with an aqueous solution comprising a non-mutagenic non-toxic iron chelating agent, such as phytic acid, diethylenetriamine pentaacetic acid (DTPA) or derivatives of these.

Treatment of asbestos and silicates to reduce their toxicity

Toxicity of asbestos is reduced by treating it with non-mutagenic non-toxic hydroxamic acid iron-chelating agents.

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Newtonville, MA, United States of America

Philip J Graceffa