Verax Corporation

Philip G Phillips

Robert C Dean, Jr

Richard A Berg

Frederick H Silver

Peter W Runstadler, Jr

Frederick Cahn

Gennaro J Maffia

Weighted microsponges formed of a porous, biostable matrix of a biocompatible polymer containing an inert weighing material are prepared suitable for use in culturing organisms in motive reactor systems. The matrix has an open to the surface pore structure with an average pore size in the range of from about 1 to about 150 microns and the pores occupy from about 70 to about 98% by volume of the microsponge. The microsponges have an average particle size of from about 100 to about 1000 microns and a specific gravity of above about 1.05. Biocompatible polymers that can be used are polysaccharides, proteins and synthetic polymers and the weighing material can be metals, metal alloys, metal oxides or ceramics.

Weighted microsponge for immobilizing bioactive material

Weighted collagen microsponges having a highly crosslinked collagen matrix are described suitable for use in culturing organisms in motive reactor systems. The microsponges have an open to the surface pore structure, and pore sizes and volumes suitable for immobilizing a variety of bioactive materials. The microsponges also have an average particle size in the range of about 100 to about 1000 microns and a specific gravity above about 1.05.

Weighted collagen microsponge for immobilizing bioactive material

Weighted collagen microsponge for immobilizing bioactive materials

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Norwich, VT, United States of America

Philip G Phillips