Optiscan Biomedical Corporation

Philip C Hartstein

James Roswell Braig

Peter Rule

Bernhard B Sterling

Jennifer H Gable

Kenneth I Li

Daniel S Goldberger

Robert D Gaffney

Julian M Cortella

Mark D Agostino

Kenneth G Witte

Martin J Fennell

Peng Zheng

W Dale Hall

Roger O Herrera

Ken Li

Heidi M Smith

David C Klonoff

Ken G Witte

Mike A Munrow

Bernard B Sterling

David Klonoff

Jane J Sheill

A reagentless whole-blood analyte detection system that is capable of being deployed near a patient has a source capable of emitting a beam of radiation that includes a spectral band. The whole-blood system also has a detector in an optical path of the beam. The whole-blood system also has a housing that is configured to house the source and the detector. The whole-blood system also has a sample element that is situated in the optical path of the beam. The sample element has a sample cell and a sample cell wall that does not eliminate transmittance of the beam of radiation in the spectral band.

Analyte monitoring systems and methods

In vitro determination of analyte levels within body fluids

Device and method for in vitro determination of analyte concentration within body fluids

A method determines an analyte concentration in a sample. The sample includes the analyte and a substance. The method includes providing absorption data of the sample. The method further includes providing reference absorption data of the substance. The method further includes calculating a substance contribution of the absorption data. The method further includes subtracting the substance contribution from the absorption data, thereby providing corrected absorption data substantially free of a contribution from the substance.

Method of determining analyte concentration in a sample using infrared transmission data

Device and method for in vitro determination of analyte concentrations within body fluids

Reagent-less whole-blood glucose meter

A method uses spectroscopy to determine an analyte concentration in a sample. The method includes producing an absorbance spectrum of the sample. The method further includes shifting the absorbance spectrum to zero in a wavelength region. The method further includes subtracting a water or other substance contribution from the absorbance spectrum.

Pathlength-independent methods for optically determining material composition

A spectroscopic sample holder comprises a microporous sheet. The microporous sheet has a top surface, a bottom surface substantially parallel to the top surface, and at least one side surface oriented substantially perpendicular to the top and bottom surfaces. The side surface forms an exposed transit opening configured to contact a material sample and distribute the contacted material sample into the microporous sheet. The spectroscopic sample holder further comprises a first planar support member positioned on, and substantially parallel to, the top surface of the microporous sheet. The spectroscopic sample holder further comprises a second planar support member positioned on the bottom surface of the microporous sheet, and oriented substantially parallel to the first planar support member.

Layered spectroscopic sample element with microporous membrane

Growing community of inventors

Cupertino, CA, United States of America

Philip C Hartstein