Dignity Sciences Limited

Ds Biopharma Limited

Basf Pharma (callanish) Limited

Equateq Limited

Basf Pharma Limited

Phil Knowles

Adam Kelliher

Angus Morrison

The present invention provides a compound which is a polyunsaturated fatty acid (PUFA) derivative of formula (I), or a pharmaceutically acceptable salt, or solvate thereof, for use in treating various skin disorders.

Topical compositions comprising polyunsaturated fatty acids

Use of pufas for treating skin inflammation

The present disclosure provides topical compositions comprising a polyunsaturated fatty acid (PUFA) derivative of formula (I): or a salt thereof.

Use of PUFAS for treating skin inflammation

There is provided a process for purifying a fatty acid, which process comprises reacting a fatty acid with a lithium salt in a first solution and under conditions to allow formation of a precipitate of a lithium salt of the fatty acid; isolating the precipitate; dissolving the precipitate in a second solution followed by separation of the organic and aqueous layers so formed; and evaporating the organic layer to isolate the purified fatty acid. There is also provided a process for increasing the length of a fatty acid, and the use of a lithium salt to purify a fatty acid.

Process for preparing and purifying fatty acids

Use of PUFAs for treating skin inflammation

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Cumbria, United Kingdom

Phil Knowles