Proscan Rx Pharma Inc.

Immunotec Research Corporation

Immunotech Research Corporation, Ltd.

Phil Gold

Uri H Saragovi

Claudio A Cuello

Gustavo Bounous

Serge Moffett

Pierre Du Ruisseau

Nicole Bernard

Patricia A Kongshavn

Dominic Melançon

Serge Moffet

Antibodies (Ab) and antigen binding fragments capable of binding to prostate specific membrane antigen and which may be used for diagnostic and therapeutic purposes are provided herein. Formulation anti-PSMA antibodies which are stable under extreme storage condition are also provided.

Antibodies against prostate specific membrane antigen

The present invention relates to novel antibodies and their use for detecting, imaging, staging, treating and monitoring of prostate cancer, and/or metastasis thereof. The present invention also relates to novel pharmaceutical compositions for the treatment of prostate cancer. Furthermore the present invention relates to assay systems and kits for detecting, imaging, staging, treating and monitoring of prostate cancer, and/or metastasis thereof.

Prostate cancer diagnosis and treatment

The present invention relates to novel mimetopes of anti-PSMA antibodies and their use for detecting, imaging, staging, treating and monitoring of prostate cancer, and/or metastatis thereof. The present invention also relates to novel pharmaceutical compositions for the treatment of prostate cancer. Furthermore the present invention relates to assay systems and kits for detecting, imaging, staging, treating and monitoring of prostate cancer, and/or metastasis thereof.

Anti-cancer therapeutic compositions containing whey protein concentrate

Undenatured whey protein concentrate is administered to HIV-seropositive individuals to elevate their blood mononuclear cells, glutathione (GSH) level, body weight and sense of well being. In addition T-helper cells concentration and their T-helper cells/T-suppressor cells ratio are slightly elevated.

Method of treatment of HIV-seropositive individuals with dietary whey

The present invention is concerned with a whey protein composition comprising a suitable concentration of whey protein concentrate wherein the whey protein concentrate contains proteins which are present in an essentially undenatured state and wherein the biological activity of the whey protein concentrate is dependent on the overall amino acid and small peptides pattern resulting from the contribution of all its protein components and a method of producing said whey protein composition. The invention also relates to several applications of said composition.

Biologically active undenatured whey protein concentrate as food

Biologically active whey protein concentrate

This invention provides a method of improving the humoral immune response or increasing the concentration levels of glutathione in mammals, which comprises administering orally to a mammal a therapeutically or a prophylactically effective amount of undenatured whey protein concentrate which has a biological activity based on the overall amino acid and associated small peptides pattern resulting from the contribution of all its protein components. A method for improving the humoral immune response in mammals also is disclosed which comprises administering orally to a mammal the combination of a vitamin supplement containing vitamin B.sub.2 in an amount in excess of minimum daily requirements and an effective amount of undenatured whey protein concentrate. This invention further provides a dietary supplement for a mammal which comprises an effective amount of vitamin B.sub.1, and B.sub.2 and a therapeutically or prophylactically effective amount of whey protein supplement.

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Westmount, Canada

Phil Gold