Basf Se Corporation

Petra Deckert

Wolfgang Siegel

Hermann Luyken

Rocco Paciello

Peter Bassler

Robert Baumann

Thomas Schaub

Gerd Haderlein

Michael Bartsch

Jens Scheidel

Andrea Misske

Stefan Rittinger

Tim Jungkamp

Ortmund Lang

Friederike Fleischhaker

Peter Pfab

Christoph Fleckenstein

Tobias Aechtner

Samuel Neto

Martin Schäfer

Uwe Stabel

Bernd Rumpf

Julia Leschinski

Klaus-Dieter Mohl

Donata Maria Fries

Peter Groll

Peter Baβler

Vaidotas Navickas

Leo Denissen

Thomas Kaeding

Bart Van De Voorde

Katrin Treier-Marxen

Andreas Schaedler

Christian Horn

Volker Wengert

Sabine Eichhorn

Matthias Fankhaenel

Stefan Robert Deibel

Matthias Fankhänel

Frank Korpjuhn

Aykan Akin

The present invention is directed to a method of purifying a protein of interest from the particulate matter of a fermentation broth comprising the step of purifying the protein of interest from the particulate matter of the fermentation broth, wherein the step of purifying the protein of interest from the particulate matter of the fermentation broth comprises one or more washing steps, which comprises contacting the particulate matter with a washing solution comprising one or more conditions that favor the solubilization of the protein of interest and/or the desorption of the protein of interest from the particulate matter.

Method of purifying a protein from fermentation solids under desorbing conditions

A process is described for preparing 3-pentenenitrile, characterized by the following process steps:

Method for producing linear pentenenitrile

The invention relates to a process for purifying crude aromatic nitro compounds which originate from the nitration of aromatic compounds, comprising the single or multiple performance of the following wash stage (a):

Process for purifying wastewaters from the workup of crude aromatic nitro compounds

A process for purifying an aqueous glyoxal solution comprising at least one acid by extractive acid removal, comprising

Process for purifying aqueous glyoxal solutions

A method for producing 3-pentenenitrile is provided that includes: (a) isomerizing an educt stream containing 2-methyl-3-butenenitrile on at least one dissolved or dispersed isomerization catalyst to form a stream (1), which contains the isomerization catalyst(s), 2-methyl-3-butenenitrile, 3-pentenenitrile and (Z)-2-methyl-2-butenenitrile; (b) distilling the stream (1) to obtain a stream (2) as the overhead product, which contains 2-methyl-3-butenenitrile, 3-pentenenitrile and (Z)-2-methyl-2-butenenitrile and a stream (3) as the bottom product, which contains the isomerization catalyst(s); (c) distilling the stream (2) to obtain a stream (4) as the overhead product, which is enriched with (Z)-2-methyl-2-butenenitrile in comparison to stream (2), and a stream (5) as the bottom product, which is enriched with 3-pentenenitrile and 2-methyl-3-butenenitrile in comparison to stream (2); (d) distilling stream (5) to obtain a stream (6) as the bottom product, which contains 3-pentenenitrile and a stream (7) as the head product containing 2-methyl-3-butenenitrile.

Processes for obtaining aromatic hydrocarbons from a hydrocarbon mixture a1. Mixture a1 is extractively distilled with extractive solvent a2 producing mixture bl comprising solvent a2, aromatic hydrocarbons and high boilers, and nonaromatic hydrocarbon mixture b2. Mixture b1 is distilled to aromatic hydrocarbon c1 and solvent comprising high boilers c2. Substream dl is removed from c2 and c2 is recycled to extractive distillation. Substream d1 is extracted with water producing aqueous phase e1 and organic phase e2. Aqueous phase e1 is distilled and purified solvent a2 is recovered and recycled into extractive distillation of mixture b1. Substream e2' is removed from organic phase e2 and recycled into extractive distillation of mixture b1. The amount of organic phase e2&#x2032; is such that when d1 comprising solvent, high boilers, water and circulated stream e2&#x2032; is dispersed, aqueous extract phase e1, forms a disperse phase and organic phase e2 a continuous phase.

Method for obtaining aromatic hydrocarbons from a hydrocarbon mixture

Processes for obtaining aromatic hydrocarbons from a hydrocarbon mixture comprising aromatic and nonaromatic hydrocarbons and high boilers comprising: (A) providing a hydrocarbon mixture a1 and an extractive solvent a2, (B) extractively distilling the mixture a1 with the extractive solvent to obtain a mixture b1 of extractive solvent, the aromatic hydrocarbons, and high boilers, (C) distilling the mixture b1 to one or more fractions c1 comprising aromatic hydrocarbons and the extractive solvent c2 comprising high boilers, (D) removing a substream d1 from the extractive solvent c2, (E) extracting the substream d1 of the extractive solvent with water to obtain an aqueous extract phase e1 essentially free of high boilers and an organic phase e2 comprising the high boilers, (F) distilling the aqueous extract phase e1 and recovering the extractive solvent a2. Step (E) is preceded by a distillation in which a fraction of very high-boiling hydrocarbons is removed from substream d1.

A process for extractively removing homogeneously dissolved catalysts from a reaction effluent of a hydrocyanation of unsaturated mononitriles to dinitriles with a hydrocarbon H, including performing the steps of a) concentrating the reaction effluent before step b) by distillation at pressures of from 0.1 to 5000 mbar and temperatures of from 10 to 150&#xb0; C., b) adding a hydrocarbon H to the concentrated reaction effluent to obtain a stream I, and c) feeding stream I, without prior separation of the liquid phases, into an extraction apparatus and extracting it at a temperature T with the hydrocarbon H to obtain a stream II comprising the hydrocarbon H enriched with the catalyst and a stream III having a low catalyst content.

Extraction of nickel (0) complexes from nitrile mixtures with reduced rag formation

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Bammental, Germany

Petra Deckert