Institute of Organic Chemistry and Biochemistry Ascr, V.v.i.

Institute of Organic Chemistry and Biochemistry of the As Cr, V.v.i.

Gilead Sciences, Inc.

Palacký University in Olomouc

Institute of Organic Chemistry and Biochemistry of the Academy of Sciences of the Czech Republic

Petr Naus

Michal Hocek

Aurelie Bourderioux

Marian Hajduch

Petr Dzubak

Olga Caletkova

The invention provides compounds of formula I, wherein R, Rand Rhave values defined in the specification and a pharmaceutically acceptable salt thereof; or an optical isomer thereof; or a mixture of optical isomers, as well as compositions comprising such compounds and therapeutic methods that utilize such compounds and/or compositions.

7-deazapurine nucleosides for therapeutic uses

The invention provides compounds of formula I: wherein R, Rand Rhave values defined in the specification and a pharmaceutically acceptable salt thereof; or an optical isomer thereof; or a mixture of optical isomers, as well as compositions comprising such compounds and therapeutic methods that utilize such compounds and/or compositions.

Compounds of Formula I and a pharmaceutically acceptable salt thereof, an optical isomer thereof, or a mixture of optical isomers thereof, as well as compositions which include such compounds and therapeutic methods that utilize such compounds and/or compositions.

Substituted 7-deazapurine ribonucleosides for therapeutic uses

The invention provides compounds of formula I, wherein R1, R2 and R3 have values defined in the specification and a pharmaceutically acceptable salt thereof; or an optical isomer thereof; or a mixture of optical isomers, as well as compositions comprising such compounds and therapeutic methods that utilize such compounds and/or compositions.

The invention provides compounds of formula I: wherein Rand Rhave any of the values defined in the specification and salts thereof, as well as compositions comprising such compounds and therapeutic methods that utilize such compounds.

Growing community of inventors

Prague, Czechia

Petr Naus