Alzheon, Inc.

Aventis Pharmaceuticals Inc.

Aventisub II Inc.

Petr Kocis

Martin Tolar

John A Hey

Michal Lebl

Jeremy Yu

Kit S Lam

Viktor Krchnak

Susan Abushakra

Aidan Power

Neil William Flanzraich

Provided herein is the use of a compound of Formula (I):

Sulfopropanoic acid derivatives for treating neurodegenerative disorders

Compounds, pharmaceutical compositions, methods and kits are described for treating or preventing neurodegenerative diseases such as Alzheimer's disease.

Compositions and methods for treating and preventing neurodegenerative disorders

Tramiprosate and derivatives thereof are provided herein for treating neurodegenerative disorders such as Alzheimer's disease (AD).

Methods for treating neurodegenerative disorders

Methods of treating a disease characterized by amyloid aggregates are provided herein.

Disclosed herein are methods for treating, ameliorating, and/or preventing Alzheimer's Disease in a specific patient population using tramiprosate, valyl-3-amino-1-propanesulfonic acid, or a pharmaceutically acceptable salt thereof based upon a combination of APOE4 status and disease severity.

Methods of treating neurodegenerative disorders in a particular population

Disclosed herein are methods and compositions for treating, ameliorating, and/or preventing Alzheimer's disease in ApoE4-postitive patients using particular compounds and compositions thereof.

Growing community of inventors

Framingham, MA, United States of America

Petr Kocis