Other

Commonwealth Scientific and Industrial Research Organisation

Biotechnology Australia Pty, Ltd

Peter Willadsen

Gary Stewart Cobon

Alagacone Sriskantha

Keith Norman Rand

David Harold Kemp

George Alfred Riding

Joanna Terry Moore

Law Anthony Yorke Johnston

Law A Johnston

This invention relates to an antigen isolated from the cattle tick,and to the gene coding for that antigen and to the protein product of that gene. The antigen when used in part or in entirety as an immunogen administered to cattle as a vaccine results in the production by the cattle of an immune response which is capable of damaging ticks feeding on vaccinated cattle to such an extent that the survival of such ticks is decreased and/or the reproductive capacity of the ticks is decreased to such an extent that the antigen coded for by the gene can be used as an effective vaccine against said ticks.

DNA encoding a cell membrane glycoprotein of a tick gut

The invention relates to antigens derived from ticks and to their purification. It also relates to genes encoding such antigens and to their cloning and expression from recombinant DNA molecules. Further, the invention describes the use of purified antigens and recombinant expression products having similar biological activity to those purified antigens to provide vaccines to protect cattle against tick infestation.

Growing community of inventors

Chapel Hill, Australia

Peter Willadsen