Princeton University

Accenture Global Services Gmbh

Peter W Park

Suzanne Walker Kahne

Min Ge

Hongbin Men

Charles Nebolsky

Ryan Matthew LaSalle

Janet A Tafoya

Anouk Trudel

Garth R Andrus

Matthew J Majer

Eric R Miller

A method that includes obtaining human performance related data from at least one remotely located application service provider, organizing the data into at least one metric, preparing an interpretation of the data and providing interactive, on-line access to the data and the interpretation.

Providing human performance management data and insight

General methods for monitoring the activity of MurG, a GlcNAc transferase involved in bacterial cell wall biosynthesis, is disclosed. More particularly, the synthesis of simplified substrate analogs of Lipid I (the natural substrate for MurG), which function as acceptors for UDP-GlcNAc in an enzymatic reaction catalyzed by MurG, is described. Assays using the substrate analogs of the invention are further disclosed, which are useful for identifying a variety of other substrates, including inhibitors of MurG activity, for facilitating mechanistic and/or structural studies of the enzyme and for other uses. High throughput assays are also described.

Substrate analogs for MurG, methods of making same and assays using same

Substrate analogs that substitute for lipid I as a substrate for MurG

Growing community of inventors

East Rutherford, NJ, United States of America

Peter W Park