Lockheed Martin Corporation

Leidos Innovations Technology, Inc.

Tearlab Research, Inc.

Microlab Diagnostics, Inc.

Peter Van Ruijven

Matthew Daniel Solomon

Matthew Springer

James P Landers

Orion N Scott

Brian Root

Joan Marie Bienvenue

David Saul

Jason Paul Hayes

Michael E Egan

Douglas J South

An-Chi Tsuei

Paul Kinnon

Benjamin D Sullivan

Erol Craig Harvey

Brandon Westerberg

Steve Zmina

Melissa Lee

Derek Lee

Joanna Slowinska

Michael Wilkinson

Peter Munster

Jason Hayes

Sebastiaan Garst

Christian Potzner

Michael Egan

Systems, methods, and devices for analyzing small volumes of fluidic samples, as a non-limiting example, less than twenty microliters are provided. The devices are configured to make a first sample reading, for example, measure an energy property of the fluid sample, for example, osmolality, make a second sample reading, for example, detecting the presence or concentration of one or more analytes in the fluid sample, or make both the first sample reading and the second sample reading, for example, measuring the energy property of the fluid sample as well as detecting the presence or concentration of one or more analytes in the fluid sample.

Systems and methods for integration of microfluidic tear collection and lateral flow analysis of analytes of interest

A microfluidic cartridge can include at least one nucleic acid analysis portion. Each nucleic acid analysis portion can include a fluidic network being configured for micro-liter volumes or less, a sample input at the beginning of the fluidic network, a plurality of vent ports and fluidic channels in the fluidic network configured to effectuate hydrodynamic movement within the fluidic network, an extraction mixture reservoir in the fluidic network, a mixing chamber in the fluidic network, an amplification chamber in the fluidic network, and a separation channel in the fluidic network. A nucleic acid analyzer can be capable of performing nucleic acid analysis using the microfluidic cartridge. A nucleic acid analysis method can be performed using the microfluidic cartridge.

Microfluidic cartridge

Growing community of inventors

Glen Waverley, Australia

Peter Van Ruijven