Bruker Biospin Mri Gmbh

Universitaetsklinikum Freiburg

Universitätsklinikum Freiburg

Peter Ullmann

Johannes Schneider

Wolfgang Ruhm

Maxim Zaitsev

Jürgen Hennig

Martin Haas

Bernd Jung

A method for determining the spatial distribution of magnetic resonance signals from at least one of N subvolumes predefines a reception encoding scheme and determines unique spatial encoding for at least one of the subvolumes but not for the entire volume under examination (UV). A transmission encoding scheme is also defined, wherein encoding is effected via the amplitude and/or phase of the transverse magnetization. The temporal amplitude and phase profile of the RF pulses is then calculated and each reception encoding step is carried out I times with variations according to the I transmission encoding steps in the transmission encoding scheme. The method makes it possible to largely restrict the spatially resolving MR signal encoding and image reconstruction to subvolumes of the object under examination without the achievable image quality sensitively depending on imperfections in the MR apparatus.

Method for determining the spatial distribution of magnetic resonance signals in subvolumes of an object under examination

A method for generating a desired temporal profile of the magnetization state in an object under examination (O) during an experiment involving magnetic resonance is characterized in that at least one spatially dependent change in the magnetization state inside the object under examination (O) is predefined and spatially selective radio-frequency pulses, which allow a simultaneous and independent change in the magnetization state at locations with different stipulations, are irradiated in order to implement the predefined spatially dependent change in the magnetization state. The method permits establishment of the same desired temporal profile of the magnetization state for different regions of the object under examination despite different given experimental parameters or deliberate generation of different desired profiles of the magnetization state at different locations.

Method for generating a desired spatially variable temporal profile of the magnetization state in magnetic resonance

A method for magnetic resonance (MR) for imaging an imaging area of an object has a reconstruction image quality which depends on a spatial distribution of background phase. A background phase distribution is initially determined using an optimization algorithm having a reconstruction quality as an optimization criterion, wherein limitation of a spatial variation of a background phase offset distribution is integrated as a boundary condition in the optimization algorithm. At least one spatially selective radio frequency pulse is applied which contributes to generation of an MR signal distribution having a previously determined background phase distribution, wherein the at least one spatially selective radio frequency pulse generates the background phase offset distribution as a part of the background phase distribution. In this fashion, the reconstruction quality is improved in a manner which can be realized using available equipment.

Method for magnetic resonance imaging with optimized background phase distribution

A method for obtaining amplitude and phase dependencies of radio frequency pulses, which are irradiated within the scope of a main magnetic resonance experiment for generating a predetermined n-dimensional spatial distribution (n&#x3e;=1) of transverse magnetization in an object by means of at least one radio frequency transmitting antenna of a magnetic resonance measuring system in combination with spatially and temporally varying additional magnetic fields which are superimposed on the static and homogeneous base field of the magnetic resonance measuring system and change the transverse magnetization phase in the object in dependence on location and time is characterized in that, prior to performance of the main experiment, a preparational measurement is performed in which the change with time of the transverse magnetization phase in the object under the action of the additional magnetic fields is measured in a position-resolved fashion and the amplitude and phase dependencies of the radio frequency pulses for the main experiment are calculated on the basis of this change with time of the transverse magnetization phase, which is measured in a position-resolved fashion. In this fashion, experimental imperfections in the form of unintentional additional magnetic fields can be measured, taken into consideration and compensated for.

Method for obtaining amplitude and phase dependencies of RF pulses for spatially selective excitation

A method for position dependent change in the magnetization in an object, according to a requirement in a magnetic resonance measurement, wherein radio-frequency pulses are irradiated in conjunction with supplementary magnetic fields that vary in space and over time and are superposed on the static and homogeneous basic field of a magnetic resonance measurement apparatus along a z-direction, is characterized in that non-linear supplementary magnetic fields are used, whose spatial gradient of the z-component is not constant at least at one instant of the irradiation, and that the radio-frequency pulses to be irradiated are calculated in advance, wherein progressions over time of the field strengths of the supplementary magnetic fields in the region of the object that are calculated and/or measured position-dependently are included in this calculation. This enables change in the magnetization with an at least locally spatially higher resolution and/or shorter irradiation duration of the RF pulses and supplementary magnetic fields than is feasible with linear supplementary magnetic fields produced by conventional gradient systems. In particular, this is possible under the technical and physiological conditions that currently constrain the performance of the known methods using linear supplementary fields.

Method for position dependent change in the magnetization in an object in a magnetic resonance experiment

A method for time-resolved imaging of N-dimensional magnetic resonance (=MR) with the following steps:

Method for accelerating data acquisition in dynamic magnetic resonance measurements (MRT) using parallel imaging

A method for determining amplitude and phase dependencies of radio frequency pulses that are irradiated during traversal of a defined k-space trajectory to produce a spatial pattern of the transverse magnetization in an MR experiment using at least one RF transmission antenna, is characterized in that, in a calibration step, a set of basic pulses is defined, each basic pulse is irradiated individually, the specified k-space trajectory is traversed and at least one set of basic patterns is produced by detection of the MR signals thus excited, which in a range to be examined of the object, are proportional to the complex transverse magnetization produced, wherein the k-space trajectory is traversed fully identically every time at least from the beginning of the irradiation of each basic pulse, and, in a calculation step, a defined target pattern is approximated with a linear combination of the basic patterns of a set or with a mathematical association of linear combinations, with which, within each set, the basic patterns are identically combined, and the amplitude and phase dependencies to be determined are obtained as the corresponding linear combination of the basic pulses. Experimental imperfections can be intrinsically compensated for in this way.

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Karlsruhe, Germany

Peter Ullmann