Exiqon A/s

Peter Stein Nielsen

Sakari Kauppinen

Søren Morgenthaler Echwald

Lars Kongsbak

Peter Mouritzen

Nana Jacobsen

Mikkel Nørholm

Niels Tolstrup

Tobias Mourier

Søren Mørk

Peter Arctander

Niels Tommerup

Carsten Alsbo

Henrik Vissing

Daniel C Jeffares

The invention features improved nucleic acids and methods for expression profiling of mRNAs, identifying and profiling of particular mRNA splice variants, and detecting mutations, deletions, or duplications of particular exons or other splice variants, e.g., alterations associated with a disease such as cancer, in a nucleic acid sample, e.g., a biological sample or a patient sample.

Oligonucleotides useful for detecting and analyzing nucleic acids of interest

The invention relates to ribonucleic acids, probes and methods for detection, quantification as well as monitoring the expression of mature microRNAs and small interfering RNAs (siRNAs). The invention furthermore relates to methods for monitoring the expression of other non-coding RNAs, mRNA splice variants, as well as detecting and quantifying RNA editing, allelic variants of single transcripts, mutations, deletions, or duplications of particular exons in transcripts, e.g., alterations associated with human disease such as cancer. The invention furthermore relates to methods for detection, quantification as well as monitoring the expression of deoxy nucleic acids.

Methods for quantification of microRNAs and small interfering RNAs

Growing community of inventors

Birkerød, Denmark

Peter Stein Nielsen