Bayer Aktiengesellschaft

Merck Patent Gesellschaft MIT Beschrankter Haftung

Troponwerke Gmbh & Co Kg

Peter Stadler

Karl G Metzger

Hans-Joachim Zeiler

Oswald Lockhoff

Uwe Petersen

Eckart Voss

Bernd-Wieland Kruger

Klaus Schaller

Klaus G Stunkel

Hans-Georg Opitz

Yutaka Hayauchi

Hans-Joachim Kabbe

Arnold Paessens

Karl-Georg Metzger

Hein-Peter Kroll

Gert Streissle

Helmut Brunner

Hans Paulsen

Bodo Junge

Harald Horstmann

Martin Scheer

Friedrich Berschauer

Peter Roessler

Edgar P Mohring

Anno De Jong

Wolfgang Gau

Bernhard Pelster

Samir Samaan

Wolfgang Koebernick

Volker Klimetzek

Polkhard Iodter

Rolf Jansen

Peter Taylor

A N-glycosylamide derivative of the formula (I) ##STR1## in which R.sup.1 denotes hydrogen or a saturated or mono- or polyunsaturated alkyl radical with one to 50 carbon atoms,

N-glycosylamide derivatives, processes for their preparation and their

Compounds of the formula ##STR1## in which R.sup.1 denotes hydrogen or a saturated or singly or multiply unsaturated alkyl radical having up to 50 carbon atoms,

Novel pharmaceutically active

Compounds of the formula ##STR1## wherein R.sup.1 is hydrogen, an optionally substituted aromatic hydrocarbon radical, an aralkyl radical or an optionally substituted aliphatic hydrocarbon radical having up to 45 C atoms,

Immune system-stimulating N-glycosylated ureas and carbamates

A method of combating rheumatic diseases which comprises administering to a patient afflicted therewith an amount effective to combat such disease of a compound of the formula ##STR1## in which Z is a glycosyl radical bonded via the anomeric carbon atom,

N-glycosylated carboxylic acid derivatives as agents for combating

Novel compounds of the formula ##STR1## in which X is hydrogen or --CH.sub.2 --OR.sup.5,

Substituted O-sulphonyl-glycosylamides, processes for their preparation

Compounds of the formula ##STR1## in which R.sup.1 represents an optionally substituted, straight-chain or branched, saturated, monounsaturated or polyunsaturated alkyl radical, an optionally substituted, saturated or one- or polyunsaturated cycloalkyl radical or an optionally substituted aryl radical or aralkyl radical,

Phosphorylated glycosyl-amides, -ureas, -carbamates and -thiocarbamates

The invention relates to N-glycosylated carboxamide derivatives of Formula I which are useful for influencing the body's inherent defenses, e.g. for increasing immune system antibodies. Also included in the invention are compositions containing said N-glycosylated carboxamide derivative of Formula I as active ingredients and methods for the use of said compounds and compositions.

N-glycosylated carboxamide derivatives and their use for influencing the

Growth of animals is promoted by inclusion in their feed of compounds of the formula ##STR1## in which Z is a glycosyl radical bonded via the anomeric carbon atom,

N-glycosylated carboxamide derivatives as growth-promoters in livestock

Compounds of the formula ##STR1## in which R.sup.1 represents hydrogen or an optionally substituted, straight-chain or branched alkyl or mono- or poly-unsaturated alkenyl radical with in each case up to 30 C atoms,

N-acylated 1-alkylamino-1-deoxy-ketose derivatives, a process for their

Compounds of the formula ##STR1## in which X is hydrogen or the radical --CH.sub.2 OR.sup.5,

Substituted O-acylglycosylamides, pharmaceutical compositions and method

The invention relates to sisomicin derivatives of formula (I) and methods for their preparation. Also included in the invention are compositions containing said sisomicin derivatives and the use of said derivatives and compositions for the treatment of bacterial infections.

Sisomicin compounds

The invention relates to pseudotrisaccharides of Formula (I) as defined above, methods for preparing them, compositions containing them and methods for the use of said compounds and compositions.

1-N(Aminopolyhydroxyalkyl)aminoglycoside antibiotics and method of use

The invention relates to an improved process for the isolation and purification of aminoglycoside antibiotics of Formula (I) as defined herein combining selective lipophilization of the compound of Formula (I) in the crude product obtained by fermentation with controlled liquid/liquid extraction.

Process for the preparation of purified aminoglycoside antibiotics

The invention relates to selectively protected 1-N-(.omega.-aminoalkoxycarbonyl)-sisomicin derivatives and methods for their procurement. Said derivatives are useful as intermediates for the procurement of highly active antibacterial agents of low toxicity.

Selectively protected 1-N-(.omega.-aminoalkoxycarbonyl)-sisomicin

The invention relates to sisomicin derivatives defined below in Formula (I) and a process for the preparation of said derivatives. Also included in the invention are compositions containing said derivatives and methods for using said derivatives and compositions. ##STR1##

Growing community of inventors

Haan, Germany

Peter Stadler