Other

Peter S Hersh

Szymon Suckewer

Alexander J Smits

Richard A Register

Steven A Greenstein

Anatoli Morozov

John D Gelles

Gary Joseph Kunkel

Corneal augmentations designed for the amelioration of an abnormality of a cornea and methods of using them are disclosed. The corneal augmentations are shaped from corneal templates. The required arcuate 3-D shapes of the corneal augmentations are determined based on elevation maps of the cornea as well as measurements of a severity of the abnormality such as the maximum keratoconus, K-max. Shaping of the corneal augmentation is done using computer-controlled femtosecond lasers and laser ablation.

Devices for the amelioration of an abnormality of a cornea and methods of using them

Methods for the amelioration of ectatic corneal disorders using corneal augmentations are disclosed. The shape of the augmentation is determined using data obtained from mapping of a patient's cornea based on computerized corneal topography and tomography. Factors considered include the maximum keratometry and specific iso-deviation contours. In one embodiment, an augmentation is inlayed into a femtosecond created, intrastromal pocket. In a further embodiment, an onlay augmentation is positioned over a region of the cornea from which the epithelial layer has been removed. The onlay is held in place by glue, sutures, tucking under a perimeter chamfer, or some combination thereof, until the epithelial layer regrows over the augmentation. In a further embodiment, the inlay or only augmentation is followed by a post-augmentation, further reshaping of the corneal augmentation. In one embodiment, this further reshaping is photorefractive keratectomy (PRK) surgery. In another and a phototherapeutic keratectomy (PTK) surgery.

Method for the amelioration of ectatic and irregular corneal disorders

A system and method of replacing a lens to treat a cataract is disclosed. Cataractous tissue is ablated via a multi-photon process using focused, ultra-short laser pulses. Multi-photon ablation requires an energy intensity between 10to 10W/cm. Using lasers having femto-second duration pulses, this intensity is achieved with 50 micro-Joules of energy, allowing material disruption with very little heating or shock. The multi-photon ablated material is removed through a micro-channel that leads from the multi-photon ablated region to at least the surface of the eye. Once the material is removed a pre-polymer fluid is injected in to fill the void. This polymerizes into a gel once inside the lens. The polymerized, transformed material matches both the transparency to visible light and the Young's modulus of healthy lens.

Cataract removal using ultra-short pulse lasers

The invention relates to devices, compositions and methods used to improve vision and/or to treat an eye lens disease or condition. In some embodiments, the invention relates to altering or removing eye lens material for the treatment of presbyopia. In additional embodiments, the invention relates to placing compositions in a lens of an eye to improve elasticity of the lens both therapeutically by improving elasticity and/or improving refractive properties and/or prophylactically by preventing renewed stiffening and/or renewed deterioration of the lens refractive properties. In further embodiments, the invention relates to devices and methods of obtaining and analyzing data for use in altering the lens to optimize its elasticity and/or refractive properties.

Devices, methods and compositions for presbyopia correction using ultrashort pulse laser

A method and device for flapless, intrastromal keratomileusis for the correction of myopia, hyperopia and astigmatism, i.e., for vision correction by corneal reshaping without creating a flap. Ultra-short laser pulses are used to create a temporary micro-channel extending to an end point located within the cornea. A second series of ultra-short laser pulses are then delivered to photo-ablate material in the vicinity of the micro-channel end-point. The photo-ablated material may exit through the micro-channel used to deliver the laser pulses, or via a separate micro-channel. With the micro-channel oriented substantially normal to the optical axis of the cornea, and by continuing to supply the ultra-short laser pulses in the appropriate number while moving the point of ablation along the micro-channel, the photo-ablation of the intrastromal tissue may continue in a controlled fashion and the cornea reshaped in a predetermined manner without creating a flap.

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Teaneck, NJ, United States of America

Peter S Hersh