Integrated Sensors, LLC

Other

University of Michigan

Dhr, Incorporated

Peter S Friedman

Ray A Stoller

Daniel S Levin

Jonathan G Bornstein

A method for preparing a stem cell-based, human derived composition containing conditioned cell culture medium is disclosed. The method comprises culturing cells of two or more eukaryotic cell lines to form conditioned culture media, separating the cultured cells from the conditioned culture media, and combining conditioned culture media to form a bioactive composition. This composition is used to treat citrus plants that have been infected by one or more insect-vectored bacterial and/or pathogenic infections such as Citrus Greening. This method consists of applying the conditioned media one or more times to the plant. Use of this treatment may have application to a variety of other agricultural conditions.

Compositions and methods for treating citrus plants infected with bacteria and for promoting general agricultural health

Embodiments are directed generally to an ionizing-radiation beamline monitoring system that includes a vacuum chamber structure with vacuum compatible flanges through which an incident ionizing-radiation beam enters the monitoring system. Embodiments further include at least one scintillator within the vacuum chamber structure that can be at least partially translated in the ionizing-radiation beam while oriented at an angle greater than 10 degrees to a normal of the incident ionizing-radiation beam, a machine vision camera coupled to a light-tight structure at atmospheric/ambient pressure that is attached to the vacuum chamber structure by a flange attached to a vacuum-tight viewport window with the camera and lens optical axis oriented at an angle of less than 80 degrees with respect to a normal of the scintillator, and at least one ultraviolet ('UV') illumination source facing the scintillator in the ionizing-radiation beam for monitoring a scintillator stability comprising scintillator radiation damage.

Ionizing-radiation beamline monitoring system

Embodiments are directed generally to an ionizing-radiation beam monitoring system that includes an enclosure structure with at least one ultra-thin window to an incident ionizing-radiation beam. Embodiments further include at least one scintillator within the enclosure structure that is substantially directly in an incident ionizing-radiation beam path and at least one ultraviolet illumination source within the enclosure structure and facing the scintillator. At least one pixelated imaging system within the enclosure structure is located out of an incident ionizing-radiation beam path and includes at least one pixelated photosensor device optically coupled to an imaging lens.

Ionizing-radiation beam monitoring system

A transmissive ionizing-radiation beam monitoring system includes an enclosure structure with at least one ultra-thin window to an incident ionizing-radiation beam, where the ultra-thin window is highly transmissive to ionizing-radiation. Embodiments include at least one thin or ultra-thin scintillator within the enclosure structure that is substantially directly in an incident ionizing-radiation beam path and transmissive to the incident radiation beam, and at least one ultraviolet (UV) illumination source within the enclosure structure facing the scintillator. Embodiments include at least one machine vision camera within the enclosure structure located out of an incident ionizing-radiation beam path and including a camera body and lens having a projection of its optical axis oriented at an angle of incidence of 45&#xb1;35 degrees to a surface of the scintillator.

A transmissive ionizing-radiation beam monitoring system includes an enclosure structure including an entrance window and an exit window to an incident ionizing-radiation beam, where the entrance window and the exit window are highly transmissive. The system further includes a thin scintillator within the enclosure structure that is directly in an incident ionizing-radiation beam path and transmissive to the incident radiation beam and an ultraviolet ('UV') illumination source within the enclosure structure facing the scintillator for internal system calibration. Embodiments further include a UV photosensor within the enclosure structure positioned to monitor and calibrate the UV illumination source and a machine vision camera within the enclosure structure that includes a lens which views the scintillator through a close proximity mirror including a folded optical axis system located to a side of the scintillator.

An ultra-thin radiation detector includes a radiation detector gas chamber having at least one ultra-thin chamber window and an ultra-thin first substrate contained within the gas chamber. The detector further includes a second substrate generally parallel to and coupled to the first substrate and defining a gas gap between the first substrate and the second substrate. The detector further includes a discharge gas between the substrates and contained within the gas chamber, where the discharge gas is free to circulate within the gas chamber and between the first and second substrates at a given gas pressure. The detector further includes a first electrode coupled to one of the substrates and a second electrode electrically coupled to the first electrode. The detector further includes a first discharge event detector coupled to at least one of the electrodes for detecting a gas discharge counting event in the electrode.

Ultra-thin plasma panel radiation detector

A position-sensitive ionizing-particle radiation counting detector includes a first substrate and a second substrate generally parallel to the first substrate and forming a gap with the first substrate, with a discharge gas contained within the gap. The detector includes a first electrode electrically coupled to the second substrate, and a second electrode electrically coupled to the first electrode and defining at least one pixel with the first electrode. The detector further includes an open dielectric structure pattern layered over one of the first or second electrodes and a current-limiting quench resistor coupled in series to one of the first or second electrodes. The detector further includes a power supply coupled to one of the first or second electrodes and a first discharge event detector circuitry coupled to the one of the first or second electrodes for detecting a gas discharge counting event in the electrode.

Plasma panel based ionizing-particle radiation detector

A position-sensitive ionizing-radiation counting detector includes a radiation detector gas chamber having at least one ultra-thin chamber window and an ultra-thin first substrate contained within the gas chamber. The detector further includes a second substrate generally parallel to and coupled to the first substrate and defining a gas gap between the first substrate and the second substrate. The detector further includes a discharge gas between the substrates and contained within the gas chamber, where the discharge gas is free to circulate within the gas chamber and between the first and second substrates at a given gas pressure. The detector further includes a first electrode coupled to one of the substrates and a second electrode electrically coupled to the first electrode. The detector further includes a first discharge event detector coupled to at least one of the electrodes for detecting a gas discharge counting event in the electrode.

Ultra-thin plasma radiation detector

A position-sensitive ionizing-radiation counting detector includes a first substrate and a second substrate, and a defined gas gap between the first substrate and the second substrate. The first and second substrates comprise dielectrics and a discharge gas is contained between the first and second substrate. A microcavity structure comprising microcavities is coupled to the second substrate. An anode electrode is coupled to the first substrate and a cathode electrode is coupled to the microcavity structure on the second substrate. The detector further includes pixels defined by a microcavity and an anode electrode coupled to a cathode electrode, and a resistor coupled to each of the cathode electrodes. Each pixel may output a gas discharge counting event pulse upon interaction with ionizing-radiation. The detector further includes a voltage bus coupled to each of the resistors and a power supply coupled to at least one of the electrodes.

Microcavity plasma panel radiation detector

A radiation detector is formed from a plasma panel that includes a front substrate, and a back substrate that forms a generally parallel gap with the front substrate. X (column) and Y (row) electrodes are coupled by gas discharge events to define one or more pixels. Impedances are coupled to the X and Y electrodes, and a power supply is coupled to one or both types of electrodes. Discharge event detectors are coupled to the impedances.

Plasma panel based ionizing radiation detector

A position-sensitive radiation counting detector includes a first and a second substrate. A gas is contained within the gap between the substrates. A photocathode layer is coupled to the first substrate and faces the second substrate. A first electrode is coupled to the second substrate and a second electrode is electrically coupled to the first electrode. A first impedance is coupled to the first electrode and a power supply is coupled to at least one electrode. A first discharge event detector is coupled to one of the electrodes for detecting a gas discharge event in the electrode. The radiation counting detector further includes a plurality of pixels, each capable of outputting a gas discharge counting event pulse upon interaction with radiation received from the photocathode. Each gas discharge pulse is counted as having an approximately equal value.

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Toledo, OH, United States of America

Peter S Friedman