The General Hospital Corporation

Auburn University

Massachusetts General Hospital Corporation

Peter Panizzi

Ralph Weissleder

Scott A Hilderbrand

Jason R McCarthy

Matthias P Nahrendorf

Andrew D Brannen

Robert D Arnold

An animal, specimen, or imaging phantom is imaged in precise increments over at least 360 degrees. The animal, specimen, or imaging phantom is supported within a subject holder. The subject holder has an elongated portion or tube for holding securely the animal, specimen or imaging phantom. The subject holder is connected to an actuator motor driver. The actuator motor driver causes the subject holder to rotate at the precise increments, and an image of the animal, specimen, or imaging phantom is captured at each increment. The subject holder limits movement of the subject being imaged at each increment.

Devices and methods for facilitating imaging of rotating animals, specimens, or imaging phantoms

The present invention provides methods and compositions based on optical sensor conjugates that are useful for detecting reactive oxygen, reactive nitrogen, or both species that are a direct result of inflammation caused by tissue damage.

Optical sensor conjugates for detecting reactive oxygen and/or reactive nitrogen species in vivo

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Auburn, AL, United States of America

Peter Panizzi