Pharmacia & Upjohn Ab

Galt Incorporated

Amo Groningen B.v.

Peter P Huo

Stephen Q Zhou

Sverker Norrby

Christine J Liau

Sheila K Wallin

Christine J Y Liau

Disclosed herein are bioadhesive medical devices formed in whole or in part of a cohesive bioadhesive copolymer of a carboxyl functional monomer and a hydrophobic functional monomer.

Bioadhesive medical devices

Polysiloxanes suitable for the preparation of intraocular lenses by a crosslinking reaction, having a specific gravity of greater than about 1.0, a refractive index suitable for restoring the refractive power of the natural crystalline lens and a viscosity suitable for injection through a standard cannula are provided. Moreover, injectable intraocular lens material based on these polysiloxanes and methods of preparing intraocular lenses by direct injection into the capsular bag of the eye are also disclosed.

Injectable intraocular lens

An injectable intraocular lens composed of a silicone material is disclosed. The silicone lens material is polymerized from a plurality of siloxane monomers. The silicone lens material has a specific gravity great than 1.0 and a refractive index of a natural lens.

Reduced trauma medical implants and methods for their use are disclosed wherein at least a portion of the implant is formed of a stretch-crystallizable elastomeric material formulated to exhibit the property of stretch crystallization upon substantial elongation of the implant to form stable, small-incision implant configurations having at least one dimension substantially reduced for insertion through a surgical incision that is small relative to the incision size necessary to implant the unstretched implant. Exemplary embodiments include intraocular implants formed of optically clear, high refractive index stretch-crystallizable silicone elastomers formulated to stretch crystallize at near ambient temperatures upon elongations greater than or equal to 300% and to recover their original configuration immediately upon exposure to body temperature following implantation.

Growing community of inventors

Irvine, CA, United States of America

Peter P Huo