Novartis Ag

Sandoz Gmbh

Irm LLC

Novartis Pharma Gmbh

Peter Nussbaumer

Anton Stutz

Klemens Högenauer

Nathanael Schiander Gray

Shifeng Pan

Rainer Albert

Lawrence Blas Perez

Yuan Mi

Claus Ehrhardt

Wenqi Gao

Klaus Hinterding

Peter Ettmayer

Erwin Paul Schreiner

Andreas Billich

Wei Wang

Sophie Lefebvre

Ingeborg Schuster

Kenneth Richad La Montagne

Birgit Dorobek

Fan Yi

Federic Zecri

Wenqui Gao

Kenneth Richard La Montagne

Ying Fan

Frédéric Zecri

A compound of formula (I) wherein R, R, R, Rand Rare as defined in the specification, processes for their production, their uses, in particular in transplantation, and pharmaceutical compositions containing them. 

Amino-propanol derivatives

Compounds of formula I, wherein X, a, b, R, R, R, Rand Rare as defined in the specification, processes for their production, their uses and pharmaceutical compositions containing them.

Aminopropanol derivatives as sphingosine-1-phosphate receptor modulators

The present invention relates to biphenylyl derivatives, processes for their production, their uses and pharmaceutical compositions containing them. Compounds according to the present invention are based upon the chemical formula: wherein the substituents have the values mentioned herein.

Bis-aromatic alkanols

The invention concerns momoclonal antibodies to terbinafine in free base or salt form, immunogenic conjugates suitable for preparing them, hybridoma capable of producing them, and corresponding assay kits. The antibodies can be prepared by administering to an appropriate animal an immunogenic conjugate of a suitable derivative of terbinafine covalently linked to an immonogen, recovering antibody-producing cells sensitized to the conjugate, immortalizing the antibody-producing cells, selecting a resultant immortalized cell line, and recovering the resultant antibodies therefrom. They are indicated for use in particular in the measurement of terbinafine tissue concentration and distribution in bodily fluids or compartments, especially nails.

Specific monoclonal antibody against terbinafine

Chromanone and thiochromanone compounds

Trisubstituted phenyl derivatives

The invention concerns the compounds of formula I ##STR1## wherein the substituents have various significances, in free form and, where such forms exist, in salt form. The compounds have potent antihyperproliferative/antiinflammatory and anticancer activity.

Bis(phenyl)ethane derivatives

Compounds of formula I ##STR1## wherein R.sub.1 represents a group of formula ##STR2## and R.sub.2 represents hydrogen or lower alkyl, or

Amine derivatives, processes for their production and their use

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Maria Enzersdorf, Austria

Peter Nussbaumer