St. Jude Medical, Cardiology Division, Inc.

St. Jude Medical, Inc.

Medtronic, Inc.

Mediview Xr, Inc.

Peter Nicholas Braido

Mina Safwat Fahim

Andrea L McCarthy

Julia Ann Schraut

Thomas M Benson

Yousef F Alkhatib

Kent J Smith

Paul Edward Ashworth

Andrea N Para

Rubem L Figueiredo

Jacob John Daly

Steven Frederick Anderl

Theodore Paul Dale

Mathias Charles Glimsdale

Mark Krans

Aaron J Chalekian

Ott Khouengboua

Ross D Hinrichsen

Neelakantan Saikrishnan

Saravana B Kumar

Xue Mei Li

Julia Ann Neuman

Aditee Kurane

Gaurav Satam

Bruce Moseman

Daniel Coyle

Chad Qingshen Cai

Ryan Kenneth Buesseler

Sounthara Khouengboua

Bob Allan

Mary Johnson

Lise LaChance

Kristen T Morin

Ramji T Venkatasubramanian

Loell Boyce Moon

Steven D Kruse

Katherine A Ahmann

Jeffrey J Allison

Jaishankar Kutty

Ralph Joseph Thomas

Jason White

Nicolas Coulombe

William C Harding

Gregory James Dakin

Chad Joshua Green

Gary W Geiger

Peter J Ness

Morgan Low

Monica M Bolin

Paul Stanley Addison

Dan Wittenberger

Jean-Pierre Lalonde

Zhongping C Yang

Shantanu Sarkar

Randal C Schulhauser

Jeffrey Harold Yanof

XueMei Li

Steve D Kruse

Jeffrey J Jannicke

Megan L Harris

Sounthara (ott) Khouengboua

Shinichi Joseph Takayama

Max L Balter

Joseph D Brannan

Julia Schraut

Ross Daniel Hinrichsen

Angela Burgess

Andrea Louise McCarthy

Aydan Thomas Hanlon

Julia A Neuman

Julia A Neumann

Gaurav C Satam

Bruce A Moseman

Kent Joseph Smith

Aditee A Kurane

Jaishankar K Kutty

Mary B Johnson

Jason A White

Mark Kranz

Lise Lachance

Daniel P Coyle

Embodiments of the present disclosure may include a method for planning and performing an interventional procedure on a patient, the method including steps of providing an augmented reality system, a tracked instrument, a first image acquisition system, a second image acquisition system, and a computer system with a processor and a memory, the tracked instrument having a plurality of sensors to provide a tracked instrument dataset, the first image acquisition system, and the computer system in communication with the augmented reality system, the tracked instrument, the first image acquisition system, and the second image acquisition system. Embodiments may also include acquiring, by the first image acquisition system, the first holographic image dataset from the patient. Embodiments may also include acquiring, by the second image acquisition system, the second holographic image dataset from the patient.

Planning and performing three-dimensional holographic interventional procedures with holographic guide

Novel tools and techniques are provided for presenting patient information to a user. In some embodiments, a computer system may: receive device data associated with one or more devices configured to perform a cardiac blood flow procedure to provide effective blood flow through a heart and to or from blood vessels of a patient; receive one or more imaging data associated with one or more imaging devices configured to generate images of one or more internal portions of the patient; analyze the device data and the imaging data; map the device data and the imaging data to a multi-dimensional representation of the one or more internal portions of the patient; generate one or more image-based outputs based at least in part on the mapping; and present, using a user experience ('UX') device, the generated one or more image-based outputs.

Presentation of patient information for cardiac blood flow procedures

Novel tools and techniques are provided for implementing intelligent assistance ('IA') or extended intelligence (“EI”) ecosystem for pulmonary procedures. In various embodiments, a computing system might analyze received one or more first layer input data (i.e., room content-based data) and received one or more second layer input data (i.e., patient and/or tool-based data), and might generate one or more recommendations for guiding a medical professional in guiding a surgical device(s) toward and within a lung of the patient to perform a pulmonary procedure, based at least in part on the analysis, the generated one or more recommendations comprising 3D or 4D mapped guides toward, in, and around the lung of the patient. The computing system might then generate one or more XR images, based at least in part on the generated one or more recommendations, and might present the generated one or more XR images using a UX device.

Extended intelligence for pulmonary procedures

A prosthetic heart valve for replacing a native valve includes a collapsible and expandable stent having a proximal end and a distal end, and a valve assembly disposed within the stent, the valve assembly including a plurality of leaflets and a cuff annularly disposed about the stent. The cuff includes a surplus portion capable of forming a sealing structure having a diameter greater than a diameter of the proximal end of the stent when deployed.

Sealing structures for paravalvular leak protection

A prosthetic heart valve includes a collapsible and expandable stent having a proximal end, a distal end, an annulus section adjacent the proximal end and an aortic section adjacent the distal end, the stent including a plurality of struts. A cuff may be coupled to the stent so that a flat, bottom edge of the cuff lies adjacent the proximal end of the stent. A pattern of stitches may be circumferentially disposed around the flat bottom edge of the cuff, the pattern of stitches alternating between stitches sewn to the cuff only and stitches sewn to both the cuff and the stent.

Cuff stitching reinforcement

A prosthetic heart valve for replacing a native valve includes a stent extending between a proximal end and a distal end and including a plurality of struts forming cells, the stent having a collapsed condition and an expanded condition. At least one runner is coupled a cell, the at least one runner being configured to transition from a first configuration to a second configuration when the stent moves from the collapsed condition to the expanded condition, the at least one runner projecting radially outwardly from the cell in the second configuration. A valve assembly is disposed within the stent, the valve assembly including a plurality of leaflets, a cuff at least partially disposed on a luminal surface of the stent, and a covering material disposed on an abluminal surface of the stent and covering the at least one runner in the second configuration.

Bowed runners and corresponding valve assemblies for paravalvular leak protection

A prosthetic heart valve may include a collapsible and expandable stent extending in a flow direction between a proximal end and a distal end, a cuff attached to an annulus section of the stent and having an outer surface facing in a radial direction orthogonal to the flow direction, a plurality of prosthetic valve leaflets attached to the cuff, and a sealing structure attached to the annulus section of the stent at an inner edge of the sealing structure. The flow direction may be defined from the proximal end toward the distal end. The sealing structure may have an outer edge remote from the inner edge. The sealing structure may have a collapsed condition with the outer edge disposed adjacent the outer surface of the cuff and an expanded condition with the outer edge spaced apart from the outer surface of the cuff.

Stationary intra-annular halo designs for paravalvular leak (PVL) reduction—active channel filling cuff designs

A prosthetic heart valve having a cuff attached to a stent provides a seal for preventing paravalvular leakage. The cuff may be constructed from known sealing materials to fill in and around paravalvular leakage gaps, while continuously collapsing down into a low profile volume within the stent. The cuff is coupled circumferentially about the stent by members which may be in the nature of dimension and/or shape memory material having a tensioned and relaxed state. The members may be in the form of elongated elastic members or coiled members. When in the tensioned state, the cuff is located within the stent volume to provide a low profile prosthetic heart valve. Upon relaxing of the members, the cuff is pulled over the abluminal surface of the stent to form a cuff seal circumscribing the stent for preventing paravalvular leakage.

Stent assembly for use in prosthetic heart valves

A collapsible prosthetic heart valve includes a collapsible and expandable stent and a collapsible and expandable valve assembly. The stent has a proximal end and a distal end. A plurality of commissure points is disposed on the stent. The valve assembly is disposed within the stent and includes a plurality of leaflets. Each leaflet has a free edge. An end portion of the free edge of each leaflet is folded and sutured to a corresponding one of the plurality of the commissure points.

Leaflet suturing to commissure points for prosthetic heart valve

A method for performing a procedure on a patient includes acquiring a three-dimensional image of a location of interest on the patient and a two-dimensional image of the location of interest can be acquired. A computer system can relate the three-dimensional image with the two-dimensional image to form a holographic image dataset. The computer system can register the holographic image dataset with the patient. The augmented reality system can render a hologram based on the holographic image dataset from the patient. The hologram can include a projection of the three-dimensional image and a projection of the two-dimensional image. The practitioner can view the hologram with the augmented reality system and perform the procedure on the patient. The practitioner can employ the augmented reality system to visualize a point on the projection of the three-dimensional image and a corresponding point on the projection of the two-dimensional image during the procedure.

Augmented reality system and methods for stereoscopic projection and cross-referencing of live x-ray fluoroscopic and computed tomographic c-arm imaging during surgery

Novel tools and techniques are provided for implementing intelligent assistance ('IA') ecosystem, and, in some cases, for implementing extended reality (“XR”) for cardiac arrhythmia procedures. In various embodiments, a computing system might receive device data associated with a device(s) configured to perform a cardiac arrhythmia procedure to provide effective heart rhythm, might receive imaging data associated with an imaging device(s) configured to generate images of a portion(s) of a patient. The computing system might analyze the received device data and imaging data (collectively “received data”), might map the received data to a 3D or 4D representation of the portion(s) of the patient based on the analysis, and might generate and present (using a user experience (“UX”) device) one or more XR images or experiences based on the mapping.

Extended reality (XR) applications for cardiac arrhythmia procedures

A prosthetic heart valve includes a stent having a collapsed condition and an expanded condition. The stent includes a plurality of cells, each cell being formed by a plurality of struts, and a plurality of commissure features. The heart valve further includes a valve assembly secured to the stent and including a cuff and a plurality of leaflets, each leaflet being attached to adjacent commissure features and to the stent struts and/or the cuff.

Valve leaflet attachment in collapsible prosthetic valves

A prosthetic heart valve includes a collapsible and expandable stent, a cuff attached to an annulus section of the stent, and leaflets attached to the cuff between a first location and a second location distal to the first location in a flow direction. The stent may include struts shaped to form a plurality of cells connected to one another in annular rows around the stent. The cuff may have top and bottom edges and may occupy a first group of the cells, such that cells above the top edge are open cells at least partially devoid of the cuff. The cuff may have a landing zone extending at least one-third of a length of the stent in the flow direction between the bottom edge of the cuff and a proximal end of a most proximal cell of the open cells when the stent is in an expanded use condition.

Stent designs for prosthetic heart valves

A prosthetic heart valve (e.g., a prosthetic aortic valve) is designed to be somewhat circumferentially collapsible and then re-expandable. The collapsed condition may be used for less invasive delivery of the valve into a patient. When the valve reaches the implant site in the patient, it re-expands to normal operating size, and also to engage surrounding tissue of the patient. The valve includes a stent portion and a ring portion that is substantially concentric with the stent portion but downstream from the stent portion in the direction of blood flow through the implanted valve. When the valve is implanted, the stent portion engages the patient's tissue at or near the native valve annulus, while the ring portion engages tissue downstream from the native valve site (e.g., the aorta).

Prosthetic heart valves

A prosthetic heart valve is designed to be circumferentially collapsible for less invasive delivery into the patient. At the implant site the valve re-expands to a larger circumferential size, i.e., the size that it has for operation as a replacement for one of the patient's native heart valves. The valve includes structures that, at the implant site, extend radially outwardly to engage tissue structures above and below the native heart valve annulus. These radially outwardly extending structures clamp the native tissue between them and thereby help to anchor the prosthetic valve at the desired location in the patient.

Collapsible-expandable prosthetic heart valves with structures for clamping native tissue

Growing community of inventors

Wyoming, MN, United States of America

Peter Nicholas Braido