Hoechst Aktiengesellschaft

Dade Behring Marburg Gmbh

Behring Diagnostics Gmbh

Peter Molz

Gerd Schnorr

Heinz Jurgen Skrzipczyk

Erwin Schmidt

Stephan Neuenhofer

Guido Simons

Tonio Kinkel

Hans Wissmann

Helmut Strecker, Deceased

Heinz-Jurgen Skrzipczyk

Reinhard Kasmarker

Norbert Madry

Henning Hachmann

Hans-Peter Harthus

Gunther Nau

Heinz-Jürgen Skrzipczyk

Kurt E Weimer

Reinhard Käsmarker

Gotz Walter

The invention relates to a method for the detection of an analyte in a competitive immunoassay in the presence of an analyte derivative and first and second receptor molecules, and to a kit for carrying out this detection method.

Competitive immunoassay using complexed analyte derivatives

A method for determining the concentration of the free fraction of an active compound, present in a biological fluid, in the presence of natural binders, the free and bound fractions of the active compound being in mutual equilibrium, by

Process and test kit for determining free active compounds in biological

Method for stabilizing hydrolysis-sensitive molecules or molecular

Chemiluminescent acridinium derivatives of the formula I ##STR1## in which R.sup.4 represents a radical of the formula II or III ##STR2## and A.sup..theta., X--, R.sup.1 -R.sup.3, R.sup.5 and R.sup.6 have the stated meanings, as well as processes for the preparation of the compounds of the formula (I) and the use thereof in chemiluminescence immunoassays.

Special chemiluminescent acridine derivatives and the use thereof in

Special chemiluminescent acridine derivatives

The invention relates to a process for the stabilization of biologically active substances which are immobilized on a carrier, where the solid phase with the immobilized biologically active substance is contacted for the stabilization with a solution which contains polyanetholesulfonic acid and/or salts thereof. The biologically active substances are, in particular, antibodies.

Process for the stabilization of biologically active substances

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Mainz, Germany

Peter Molz