Novartis Ag

Irm LLC

Irm Llc, a Delaware Corp.

Peter McIntyre

Chuanzheng Song

Pamposh Ganju

Stuart Bevan

Ardem Patapoutian

Andrea Peier

Iain Fraser James

This invention provides novel genes and polypeptides of the transient receptor potential channel family, and use of these genes and polypeptides for the treatment of pain and identification of agents useful in the treatment of pain.

Transient receptor potential channel TRPM8 and its use

Transient receptor potential channel TRPV3 and its use

This invention provides novel genes and polypeptides of the VR family, identification of trkApain specific genes expressed in the DRG, and use of these genes and polypeptides for the treatment of pain and identification of agents useful in the treatment of pain.

Vanilloid receptor-related nucleic acids and polypeptides

The isolated nucleic acid encoding human vanilloid receptor, said receptor, its preparation, cells expressing said receptor and an assay for testing compounds for their potential to decrease pain in humans. The receptor is involved in detection of noxious stimuli in mammalian organisms.

Vanilloid receptor

The isolated nucleic acid encoding human vanilloid receptor, said receptor, its preparation, cells expressing said receptor and an assay for testing compounds for their potential to decrease pain in human are disclosed. The receptor is involved in detection of noxious stimuli in mammalian organisms.

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London, United Kingdom

Peter McIntyre