Schering Aktiengesellschaft

Peter Mareski

Johannes Platzek

Ulrich Niedballa

Hanns-Joachim Weinmann

Bernd Misselwitz

Bernd Raduchel

Bernd Raduechel

Andreas Muhler

The invention relates to the use of perfluoroalkyl-containing metal complexes that have a critical micelle formation concentration <10 mol/l, a hydrodynamic micelle diameter (2 Rh)>1 nm and a proton relaxivity in plasma (R )>10 l/mmol&middot;s) as contrast media in MR imaging for visualization of plaque, lymph nodes, infarcted and necrotic tissue and for independent visualization of necrotic tissue and tumor tissue.

Use of perfluoroalkyl-containing metal complexes as contrast media in MR-imaging for visualization of plaque, tumors and necroses

Perfluoroalkyl-containing complexes with polar radicals, process for their production and their use

Perfluoroalkyl-containing complexes with sugar radicals, process for their production and their use

Process for the production of perbenzylated 1-O-glycosides

Monofunctionalised EDTA, DTPA and TTHA derivatives and their use in

The invention relates to diethylenetriaminepentaacetic acid monoamide derivatives, their complexes and complex salts, containing gadolinium, dysprosium, iron or manganese, pharmaceutical agents containing these compounds, their use as contrast media and process for their production.

DTPA di-alkyl monoamides for x-ray and MRI

A process for the production of of general formula I diethylenetriaminepentacarboxylic acid monoamide derivatives ##STR1## in which E.sup.1, E.sup.2 and Z have varying meanings.

Process for the production of DTPA-monoamides of the central carboxylic

Diethylenetriaminepentaacetic acid monoamide derivatives, their complexes and complex salts, containing an element of atomic numbers 21-29, 31, 32, 39, 42-44, 49 or 57-83, pharmaceutical agents containing these compounds, their use as contrast media and process for their production.

Substituted DTPA monoamides of the central carboxylic acid group and

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Berlin, Germany

Peter Mareski