Bayer Aktiengesellschaft

Other

Bayer Chemicals Ag

Peter M&uuml;ller

Albrecht Marhold

Karen Peilst&ouml;cker

Norbert Lui

Hardy Wietzoreck

Thomas Wendel

Klaus Bittner

Marielouise Schneider

Thomas Brackemeyer

The present invention relates to a process for preparing 2-haloalkylnicotinic acids and haloalkylnicotinic acid derivatives starting from halomethyl-substituted enones and 3-dialkylaminoacrylic esters and also to intermediates of the process according to the invention.

Process for preparing 2-haloalkylnicotinic acids

The present invention relates to an improved process for preparing 2-haloacyl-3-aminoacrylic acid derivatives and pyrazole-4-carboxylic acids and derivates thereof obtainable from it.

Preparation of 2-haloacyl-3-aminoacrylic acid derivatives

Trifluoromethyl-substituted biphenylcarboxylic acids are prepared by converting methyl-substituted biphenylcarbonitriles into the corresponding trichloromethyl-substituted biphenylcarbonitriles, converting the trichloromethyl group thereof to a trifluoromethyl group and thus obtaining trifluoromethyl-substituted biphenylcarbonitriles, and preparing the corresponding carboxylic acids therefrom by hydrolysis. A number of intermediates arising during this are novel compounds.

Process for the preparation of trifluoromethyl-substituted biphenylcarboxylic acids and novel trichloromethyl-and trifluoromethyl-substituted biphenylcarbonitriles

Pretreatment of aluminum surfaces with chrome-free solutions

In an instrumentation for the production of fixing surfaces for fixing a knee joint endoprosthesis to the femoral condyle that is adjacent to the knee, and to the tibial head, provision is made for a rotary milling head, which is fixable in relation to the longitudinal axis of the femur and tibia, respectively, by fastening means and which, in relation to this longitudinal axis, is angularly adjustable in a stable stop position by being pivoted, defining milling planes, and which is displaceable in the set milling plane, covering same and working as a face milling cutter or as a cylindrical milling cutter.

Instrumentation for the production of fixing surfaces for a knee joint endoprosthesis

Process for preparing 2-(4-trifluoromethoxyphenyl)ethylamine and 4-bromomethyl-and 4-chloromethyl-1-trifluoromethoxybenzene

Fluorine-containing phenethylamines are obtained in an advantageous manner by reacting fluorine-containing bromobenzenes with acrylamide in the presence of a palladium catalyst, hydrogenating the resulting arylacrylamides catalytically and then rearranging the arylamides obtained. The invention also embraces novel arylacrylamides and novel arylamides.

Process for preparing phenethylamines and novel chemical compounds

The present invention relates to a process for preparing fluorine-containing phenethylamines which is characterized in that, in a first step, a substituted bromobenzene is reacted with an N-vinylimide in the presence of a palladium catalyst, in a second step, the resulting substituted &bgr;-iminovinylbenzene is hydrogenated catalytically and in a third step, the substituted &bgr;-iminovinylbenzene obtained in the second step is cleaved. This process also provides access to novel &bgr;-iminovinyl- and &bgr;-iminoethylbenzenes.

Growing community of inventors

Odenthal, Germany

Peter Müller

Growing community of inventors

Odenthal, Germany

Peter M&uuml;ller

Peter Müller