Schering Aktiengesellschaft

Peter Maeding

Raju Mohan

Christoph-Stephan Hilger

Richard Horuk

Joseph E Hesselgesser

Harald Dinter

Bernd Johannsen

Meredith Halks-Miller

Joerg Steinbach

Frank Fuechtner

The invention relates to a device and a process for nucleophilic fluorination of a substance, especially for synthesis of anF-labeled substance for examination using a positron emission tomograph. The device comprises an anion exchange device () for extraction of [F]fluoride ions by means of adsorption from a target fluid, whereby the anion exchange device () can be charged via a supply device () with the target fluid; and a measurement device () with a measurement chamber () for measuring initial radioactivity of the [F]fluoride ions, the anion exchange device () being arranged at least partially in the measurement chamber () of the measurement device ().

Device and process for nucleophilic fluorination

This invention is directed to the use of radiopharmaceuticals in diagnosing Alzheimer's disease. In particular the radiopharmaceuticals of the invention are able to pass through the blood-brain barrier and bind to the CCR1 receptor present in brain tissue of patients having Alzheimer's disease.

Radiopharmaceuticals for diagnosing Alzheimer's disease

Growing community of inventors

Dresden, Germany

Peter Maeding